Gene-Edited immune cells take on Hard-to-Treat cancers
NCT ID NCT05795595
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This early-phase trial tested a new treatment called CTX131 for adults with advanced solid tumors that have not responded to standard therapies. The treatment uses donor immune cells that are gene-edited to target a protein called CD70 found on cancer cells. The study enrolled 19 people with several cancer types to check safety and whether the tumors shrink.
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Research Site 1
Nashville, Tennessee, 37203, United States
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Research Site 2
St Louis, Missouri, 63110, United States
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Research Site 3
Duarte, California, 91010, United States
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Research Site 4
Durham, North Carolina, 27710, United States
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Research Site 5
Houston, Texas, 77030, United States
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Research Site 6
Boston, Massachusetts, 02215, United States
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Research Site 7
Chicago, Illinois, 60637, United States