MAJOR DEPRESSIVE DISORDER
Clinical trials for MAJOR DEPRESSIVE DISORDER explained in plain language.
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New hope for stubborn depression? Long-Term drug trial explored
Disease control TerminatedThis study aimed to see if the drug AXS-05 is safe and effective for long-term use in adults with major depression that hasn't improved with other treatments. It involved 181 participants at multiple locations. The trial was open-label, meaning both the participants and doctors k…
Matched conditions: MAJOR DEPRESSIVE DISORDER
Phase: PHASE2 • Sponsor: Axsome Therapeutics, Inc. • Aim: Disease control
Last updated Apr 01, 2026 14:43 UTC
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New hope for stubborn depression? Add-On drug trial seeks better relief
Disease control TerminatedThis study tested whether a new drug called REL-1017 could help people with major depression who were still struggling despite taking standard antidepressant medication. Participants continued their usual medication and were randomly assigned to also take either REL-1017 or a pla…
Matched conditions: MAJOR DEPRESSIVE DISORDER
Phase: PHASE3 • Sponsor: Levomecor Inc. • Aim: Disease control
Last updated Mar 31, 2026 12:10 UTC
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New hope for Tough-to-Treat depression? trial tests Add-On pill
Disease control TerminatedThis study tested whether a daily pill called REL-1017 could help people with major depression who weren't getting enough relief from their current antidepressant. Participants took either the new pill or a placebo (sugar pill) for four weeks while continuing their regular medica…
Matched conditions: MAJOR DEPRESSIVE DISORDER
Phase: PHASE3 • Sponsor: Levomecor Inc. • Aim: Disease control
Last updated Mar 27, 2026 12:38 UTC
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Brain scan could end guesswork for PTSD meds
Diagnosis TerminatedThis study tested whether a simple brainwave test could predict which veterans with PTSD or depression would respond well to common antidepressant medications (SSRIs). Researchers measured participants' brain responses to sounds before starting medication, then tracked their symp…
Matched conditions: MAJOR DEPRESSIVE DISORDER
Phase: PHASE4 • Sponsor: VA Office of Research and Development • Aim: Diagnosis
Last updated Mar 30, 2026 14:35 UTC
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New app aims to help veterans at risk of suicide by teaching them to recognize their feelings
Symptom relief TerminatedThis study tested a new program combining group education with a smartphone app designed to help veterans with serious mental illness better understand their own emotions. The goal was to see if improving this emotional awareness could help reduce their risk of suicide. The study…
Matched conditions: MAJOR DEPRESSIVE DISORDER
Phase: PHASE1 • Sponsor: VA Office of Research and Development • Aim: Symptom relief
Last updated Mar 27, 2026 12:38 UTC