MAGNETIC RESONANCE IMAGING

This study explores whether a special cardiac MRI can detect complications after heart transplantation without the need for invasive biopsies or angiography. Researchers will scan 247 adults and children, including healthy volunteers and transplant recipients, to see if MRI measu…

This study is testing whether a simpler type of MRI, called biparametric MRI (bpMRI), can improve prostate cancer screening in men at high risk, such as Black men or those with a family history of the disease. The researchers will combine bpMRI with standard PSA blood tests to se…

This study looks at whether acupuncture can reduce pain in people with sickle cell disease. Researchers will also use brain scans and other tests to understand how acupuncture works. The study involves 120 participants aged 14 to 80 who have chronic pain or recent pain crises.

This study looks at how quickly gadolinium, a contrast agent used in some MRIs, leaves the body through urine. Researchers will collect urine samples from 60 adults before and up to 2.5 hours after their MRI. The goal is to better understand the body's elimination of this substan…

This study aims to improve MRI technology for imaging the brain. Researchers will test new scanning methods on 1,100 healthy adults aged 18 and older. Participants will have yearly MRI scans and may perform simple tasks like listening to sounds or tapping fingers. The goal is to …

This study tests whether a 4-week ketogenic diet changes how the brain responds to alcohol. Twenty adults will follow the diet and undergo alcohol tolerance tests and brain scans before, during, and after the diet. The goal is to understand how ketosis affects alcohol metabolism …

This study explores why ketamine, a fast-acting antidepressant, works better in people with a family history of alcohol use disorder. Researchers will give a single low-dose ketamine infusion to 60 adults with treatment-resistant depression while scanning their brains with powerf…

This study is testing a new MRI method called T1rho that can take detailed pictures of the brain without needing a dye injection. Researchers will scan 30 healthy adults to measure what normal brain tissue looks like with this technique. The goal is to create a baseline of health…

This study explores whether using MRI scans before each radiation treatment is practical and helpful for people with liver or pancreatic cancer. About 30 participants will receive up to 5 extra MRIs alongside their standard radiation therapy. Researchers will measure patient sati…

This study looks at how brain blood flow changes when healthy adults aged 55-69 breathe differently or shift posture, using MRI scans. Participants will also receive a single dose of prazosin or a placebo to see how it affects blood flow. The goal is to better understand the brai…

This study aims to test and improve the way 3T MRI scanners capture images of the brain. Researchers will work with 230 healthy adults to optimize scanning sequences, reduce image artifacts, and ensure high-quality data for future research. The goal is to make MRI protocols more …

This study explores whether a special MRI technique called 3D magnetic resonance elastography (MRE) can accurately measure the stiffness of pancreatic tumors and surrounding scar tissue. Researchers will enroll 200 adults with pancreatic cancer to see if these stiffness measureme…

This study is following 500 people with cerebral small vessel disease (CSVD) to see how their genes affect their brain scans, symptoms, and health over time. Participants get genetic testing and MRI scans at the start and again after 1-2 years. The goal is to better understand th…

This study looks at how well pelvic organs move in women with endometriosis using dynamic MRI. Researchers want to see if measuring this movement can help diagnose the disease better and explain why some treatments don't work. About 52 women with suspected endometriosis will take…

This study looks at how the brain's blood vessels respond when blood flow drops suddenly. Healthy adults aged 20-40 will undergo MRI scans while doing breathing exercises and a simulated postural change. Some will receive a single dose of prazosin, a blood pressure drug, to see h…

This study tests a decision aid designed to help Black and Latina women at high risk for breast cancer make informed choices about whether to get a breast MRI in addition to their yearly mammogram. Eighty participants will be randomly assigned to receive either standard risk info…

This study is testing whether a new, very powerful 7-Tesla MRI machine can take clearer pictures of the muscles, bones, and head compared to standard 3-Tesla MRI. About 780 healthy volunteers and patients will each have a one-hour scan. The goal is to see if the higher-powered sc…

This study uses a very strong 7 Tesla MRI scanner to take detailed pictures of the neck spine. Researchers want to measure normal nerve sizes and see how the spine's blood vessels relate to nerves. About 600 adults with or without back pain will join to create a reference for hea…