Brain blood flow study aims to uncover clues about aging

NCT ID NCT06629077

Recruiting now Knowledge-focused Sponsor: University of Wisconsin, Madison Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at how brain blood flow changes when healthy adults aged 55-69 breathe differently or shift posture, using MRI scans. Participants will also receive a single dose of prazosin or a placebo to see how it affects blood flow. The goal is to better understand the brain's response to reduced blood flow, which could inform future research on age-related conditions.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Prazosin
What this could lead to: If successful, this could help scientists understand how brain blood flow changes with age and posture, potentially guiding future treatments for conditions like dizziness or fainting.
What could go wrong: This is a small, early-phase study with only 36 participants, so results may not apply to everyone. Prazosin can cause dizziness or low blood pressure.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CEREBROVASCULAR CIRCULATION MAGNETIC RESONANCE IMAGING

Contacts and locations

Locations

University of Wisconsin
RECRUITING

Madison, Wisconsin, 53705, United States

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