MRI reveals how exercise changes brain blood flow differently by age and sex

NCT ID NCT05864950

Ongoing Knowledge-focused Sponsor: University of Wisconsin, Madison Source: ClinicalTrials.gov ↗

First seen Jul 07, 2026 · Last updated Jul 14, 2026 · Updated 3 times

Summary

This pilot study uses MRI to measure brain blood flow in healthy adults aged 55-69 while they exercise at light and moderate intensities. Researchers want to see if age and biological sex influence how blood vessels in the brain respond to physical activity. Participants must be regularly active and comfortable using exercise equipment. The study aims to better understand normal brain blood flow changes during exercise.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this study could help explain how age and sex affect brain blood flow during exercise, potentially guiding future research on brain health.
What could go wrong: This is a small pilot study with only 80 participants, so results may not apply to everyone. It measures short-term changes, not long-term health outcomes.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Motor Activity

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CEREBROVASCULAR CIRCULATION MAGNETIC RESONANCE IMAGING

Contacts and locations

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Locations

University of Wisconsin-Madison

Madison, Wisconsin, 53706, United States

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