LIVER FIBROSIS
Clinical trials for LIVER FIBROSIS explained in plain language.
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Can a two-pill cocktail reverse liver damage from fatty liver disease?
Disease control CompletedThis study tested whether a combination of two drugs, dasatinib and quercetin, can reduce liver scarring in people with non-alcoholic fatty liver disease (NAFLD) and liver fibrosis. Thirty adults with biopsy-confirmed fibrosis took the drugs or a placebo for 21 weeks. The main go…
Matched conditions: LIVER FIBROSIS
Phase: PHASE1, PHASE2 • Sponsor: Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) • Aim: Disease control
Last updated May 16, 2026 23:47 UTC
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Painless liver test could spare kids from needle biopsies
Diagnosis CompletedThis study tested whether a noninvasive device called FibroScan can accurately measure liver scarring (fibrosis) in children, potentially replacing the standard but painful liver biopsy. Researchers compared the device's readings to biopsy results in 264 children with various liv…
Matched conditions: LIVER FIBROSIS
Phase: NA • Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Diagnosis
Last updated May 13, 2026 16:03 UTC
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Needle-Free liver test: MRI could replace painful biopsies
Diagnosis CompletedThis study tested a new, fully automated MRI technique to diagnose and stage liver fibrosis and inflammation without needing a needle biopsy or injected contrast dye. Researchers studied 200 adults with chronic liver disease who were already scheduled for a liver biopsy. The goal…
Matched conditions: LIVER FIBROSIS
Sponsor: Chinese University of Hong Kong • Aim: Diagnosis
Last updated May 04, 2026 16:30 UTC
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HIV drug side effects: new study probes liver scarring risk
Knowledge-focused CompletedThis study looked at liver damage in 127 HIV patients who had high liver enzymes while on antiretroviral therapy. Researchers used liver biopsies, ultrasound, and CT scans to check for scarring (fibrosis) and fat buildup. The goal was to better understand how HIV drugs may harm t…
Matched conditions: LIVER FIBROSIS
Sponsor: National Institute of Allergy and Infectious Diseases (NIAID) • Aim: Knowledge-focused
Last updated May 16, 2026 23:49 UTC
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New ultrasound technique aims to better measure liver health
Knowledge-focused CompletedThis study tested a new ultrasound technique called ARFI to measure liver stiffness in 109 people, including healthy volunteers and patients with liver conditions. The goal was to find normal stiffness values and see how reproducible the measurements are. This research helps impr…
Matched conditions: LIVER FIBROSIS
Phase: NA • Sponsor: University Hospital, Bordeaux • Aim: Knowledge-focused
Last updated May 16, 2026 23:47 UTC
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New study seeks best way to spot liver damage in thalassemia kids
Knowledge-focused CompletedThis study looked at 100 children with beta-thalassemia major and iron overload to see which tests best detect liver scarring. Researchers compared blood markers (ferritin, hepcidin) and non-invasive scores (APRI, FIB-4) against a special ultrasound (FibroScan). The goal was to f…
Matched conditions: LIVER FIBROSIS
Sponsor: Tanta University • Aim: Knowledge-focused
Last updated May 16, 2026 23:46 UTC