LIVER FIBROSIS
Clinical trials for LIVER FIBROSIS explained in plain language.
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Can a Two-Drug cocktail reverse liver scarring? early trial hints at possibility
Disease control CompletedThis study tested whether a combination of two drugs, dasatinib and quercetin, can reduce liver scarring in people with non-alcoholic fatty liver disease (NAFLD) and fibrosis. Thirty adults with biopsy-confirmed liver scarring took either the drug combo or a placebo in cycles ove…
Matched conditions: LIVER FIBROSIS
Phase: PHASE1, PHASE2 • Sponsor: Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) • Aim: Disease control
Last updated Jun 27, 2026 12:08 UTC
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No-Needle liver test: MRI may replace painful biopsies
Diagnosis CompletedThis study tested a new, fully automated MRI technique to diagnose liver fibrosis and inflammation without needing a needle biopsy or contrast dye. Researchers scanned 200 adults with chronic liver disease and compared the MRI results to standard biopsy findings. The goal is to p…
Matched conditions: LIVER FIBROSIS
Sponsor: Chinese University of Hong Kong • Aim: Diagnosis
Last updated Jun 27, 2026 11:02 UTC
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Could a quick ultrasound replace painful liver biopsies for kids?
Diagnosis CompletedThis study tested whether a noninvasive device called FibroScan can accurately measure liver scarring (fibrosis) in children, potentially replacing the need for a liver biopsy. Researchers compared FibroScan results with biopsy results in 264 children aged 6 months to 18 years wi…
Matched conditions: LIVER FIBROSIS
Phase: NA • Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Diagnosis
Last updated Jun 27, 2026 07:58 UTC
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Simple blood tests may spot liver damage in thalassemia kids
Diagnosis CompletedThis study looked at 100 children with beta-thalassemia major and iron overload to see if simple blood tests (ferritin and hepcidin) can detect liver scarring (fibrosis) as accurately as other non-invasive methods. Researchers measured these blood markers and compared them to ult…
Matched conditions: LIVER FIBROSIS
Sponsor: Tanta University • Aim: Diagnosis
Last updated Jun 26, 2026 14:15 UTC
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HIV drug side effects: new study probes liver damage risk
Knowledge-focused CompletedThis study looked at liver fibrosis (scarring) in 127 HIV patients who had high liver enzymes while on antiretroviral therapy. Participants underwent tests like liver biopsy, ultrasound, and CT scans to measure liver damage. The goal was to understand how common and severe liver …
Matched conditions: LIVER FIBROSIS
Sponsor: National Institute of Allergy and Infectious Diseases (NIAID) • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:00 UTC
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New models aim to predict liver disease in HIV patients
Knowledge-focused CompletedThis study looked at 315 HIV-positive adults to build models that predict fatty liver disease and liver scarring. Researchers used ultrasound and FibroScan tests to track liver changes over time. The goal was to better understand and identify liver problems early in people living…
Matched conditions: LIVER FIBROSIS
Sponsor: Shanghai Public Health Clinical Center • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:01 UTC
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New ultrasound technique aims to better measure liver health
Knowledge-focused CompletedThis study tested a new ultrasound technique called ARFI to measure liver stiffness in 109 people, including healthy volunteers and patients with liver conditions. The goal was to understand normal stiffness values and how they change with disease or treatment. This is an observa…
Matched conditions: LIVER FIBROSIS
Phase: NA • Sponsor: University Hospital, Bordeaux • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:33 UTC
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New Free-Breathing MRI could make liver scans easier for kids
Knowledge-focused CompletedThis study tested new MRI and MRE techniques that let children breathe normally during scans, instead of holding their breath. The goal was to measure liver fat and stiffness more comfortably and accurately in kids with fatty liver disease. 135 children aged 6-17 took part, and t…
Matched conditions: LIVER FIBROSIS
Sponsor: University of California, Los Angeles • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:00 UTC