Simple blood tests may spot liver damage in thalassemia kids

NCT ID NCT07153926

Completed Diagnosis Sponsor: Tanta University Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jun 26, 2026 · Updated 1 time

Summary

This study looked at 100 children with beta-thalassemia major and iron overload to see if simple blood tests (ferritin and hepcidin) can detect liver scarring (fibrosis) as accurately as other non-invasive methods. Researchers measured these blood markers and compared them to ultrasound-based elastography and calculated scores. The goal is to find a reliable, needle-free way to monitor liver health in these children.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this could lead to simpler, non-invasive blood tests to detect liver damage in children with thalassemia, reducing the need for liver biopsies.
What could go wrong: This is a small, completed observational study, not a treatment trial. The results may not apply to all children or other conditions, and the tests may not be accurate enough to replace current methods.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

beta thalassemia beta-thalassemia major cirrhosis of liver fibrotic liver disease Iron Overload iron poisoning

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

BETA-THALASSEMIA MAJOR LIVER FIBROSIS

Contacts and locations

Locations

Tanta University Hospitals

Tanta, Gharbyea, 31516, Egypt

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