LIVER FIBROSIS

This large, 5-year study aims to see if adding the drug Hydronidone to standard antiviral therapy can prevent serious liver complications in people with chronic hepatitis B who already have liver scarring (fibrosis). It will involve about 1,200 adults and compare Hydronidone agai…

This study aims to understand if having high levels of uric acid in the blood is connected to developing fatty liver disease and liver scarring in obese adults. Researchers will observe 111 participants to see how common fatty liver is in this group and measure their uric acid le…

This is an early-stage study to understand how a new drug capsule called Hydronidone moves through the body. It will test the drug's safety and how it is processed in 138 healthy volunteers. The goal is to gather information to support future studies in people with liver fibrosis…

This study aims to find out how common and severe fatty liver disease is in adults living with type 1 diabetes in Quebec. Researchers will measure liver fat and scarring in 100 participants during a single visit to see if weight plays a role. The goal is to identify people who ma…

This is an early safety study to understand how a new drug for liver fibrosis, called hydronidone, is processed by the body in people with different levels of liver damage. It will enroll 30 people, including those with mild to moderate liver impairment and others with healthy li…