Can a new pill stop liver damage in hepatitis b patients?

NCT ID NCT07412236

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests a drug called hydronidone in people with liver scarring (fibrosis) from chronic hepatitis B. About 1,200 adults will take either hydronidone or a placebo, along with standard antiviral therapy, for up to 5 years. The goal is to see if hydronidone can prevent serious liver problems like cirrhosis, liver cancer, or the need for a transplant.

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Conditions

The condition(s) this trial relates to.

cirrhosis of liver fibrotic liver disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine

    Shanghai, China

    Contact