KIDNEY TRANSPLANT

This study tests whether giving specific blood pressure drugs based on a patient's circulation type during kidney transplant surgery improves how the body responds to fluids. Researchers will monitor 255 adults and assign drugs like vasopressin or norepinephrine based on real-tim…

This early study tests a new medicine called TNX-1500 in 5 people who get a kidney transplant. The goal is to see if it is safe and can help prevent the body from rejecting the new kidney. Participants will be followed for one year to check for side effects and signs of rejection…

This study tests whether using a potassium-enriched salt substitute (75% regular salt, 25% potassium chloride) instead of regular table salt can help control blood pressure in kidney transplant recipients. About 80 participants will use either the special salt or regular salt at …

This study will test a new blood test called GraftAssure that measures DNA from the donor kidney in the recipient's blood. The goal is to see if this test can detect rejection more accurately than current methods. Researchers will enroll 5,000 kidney transplant patients and follo…

This study tests whether an IDO-1 inhibitor can safely prevent Epstein-Barr virus (EBV) infection in kidney transplant recipients who have never had EBV but receive a kidney from an EBV-positive donor. Nine participants will receive either the drug or a placebo for 28 days, along…

This study looks at whether taking the antibiotic TMP-SMX for a full year after a kidney transplant can prevent urinary tract infections (UTIs) better than stopping after 6 months. Fifty children and young adults who recently had a kidney transplant will either keep taking TMP-SM…

This study looks at whether testing the liquid used to preserve donor livers and kidneys can predict infections in recipients. Researchers will check if bacteria or fungi in that fluid match infections that develop after transplant. The goal is to see if this simple test could he…

This study tests whether an instructional video about medication management can reduce errors in kidney transplant patients compared to standard verbal instructions. About 308 adult patients at Erasmus MC will be randomly assigned to watch the video or receive usual teaching. Res…

This study tests whether a kidney transplant-specific comprehensive geriatric assessment (KT-CGA) can improve how older adults (60+) are evaluated for kidney transplants. Fifty participants will either receive the KT-CGA plus usual care or usual care alone. The goal is to see if …

This study tests whether a digital program (videos, texts, and optional phone support) can help people with kidney failure get more inquiries from potential living donors. About 430 adults referred for a kidney transplant will be randomly assigned to get the program with or witho…

This study will collect data from 300 kidney transplant patients who receive kidneys from older or higher-risk donors. The kidneys are kept on a machine that pumps cold fluid through them before transplant. Researchers will see if the machine's readings (like flow and pressure) c…

This study looks at two standard methods of stitching the kidney artery during a living donor kidney transplant: interrupted sutures and continuous sutures. Researchers will review past cases and follow 70 new adult patients at Assiut University to see which technique leads to sh…

This study will examine why some people with chronic kidney disease in Spain may have a harder time getting a kidney transplant than others. Researchers will survey 3,000 patients and interview doctors and patients to understand barriers like age, income, or where someone lives. …

This study will analyze the DNA and chemical marks on DNA of 200 children who have had a liver or kidney transplant. Researchers want to find genetic clues that might explain why some children develop serious complications like organ rejection, infections, or cancer after transpl…