Could a few more months of antibiotics keep kidney transplant patients infection-free?
NCT ID NCT07106125
First seen Nov 01, 2025 · Last updated Jun 22, 2026 · Updated 28 times
Summary
This study looks at whether taking the antibiotic TMP-SMX for a full year after a kidney transplant can prevent urinary tract infections (UTIs) better than stopping after 6 months. Fifty children and young adults who recently had a kidney transplant will either keep taking TMP-SMX or switch to a placebo for an extra 6 months. The researchers will track infections, side effects, and how well participants stick with the medication.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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University of California, San Francisco
San Francisco, California, 94158, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
trimethoprim-sulfamethoxazole (TMP-SMX)
What this could lead to
If it works, this could show that extending antibiotic use reduces UTIs in young kidney transplant recipients.
What could go wrong
This is a small pilot study (50 people) testing feasibility, not a large trial. It may not prove effectiveness, and longer antibiotic use carries risks like side effects or resistance.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.