Could a few more months of antibiotics keep kidney transplant patients infection-free?
NCT ID NCT07106125
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looks at whether taking the antibiotic TMP-SMX for a full year after a kidney transplant can prevent urinary tract infections (UTIs) better than stopping after 6 months. Fifty children and young adults who recently had a kidney transplant will either keep taking TMP-SMX or switch to a placebo for an extra 6 months. The researchers will track infections, side effects, and how well participants stick with the medication.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- trimethoprim-sulfamethoxazole (TMP-SMX)
- What this could lead to
- If it works, this could show that extending antibiotic use reduces UTIs in young kidney transplant recipients.
- What could go wrong
- This is a small pilot study (50 people) testing feasibility, not a large trial. It may not prove effectiveness, and longer antibiotic use carries risks like side effects or resistance.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
University of California, San Francisco
San Francisco, California, 94158, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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