Smart drug matching during kidney transplant could boost success

NCT ID NCT07633600

Not yet recruiting Disease control Sponsor: Jennifer Cutler Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether giving specific blood pressure drugs based on a patient's circulation type during kidney transplant surgery improves how the body responds to fluids. Researchers will monitor 255 adults and assign drugs like vasopressin or norepinephrine based on real-time heart and blood vessel measurements. The goal is to see if this personalized approach leads to better blood pressure control and fluid management during the operation.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Vasopressin, Norepinephrine, Calcium Chloride, Dopamine
What this could lead to: If successful, this could lead to better blood pressure and fluid management during kidney transplant surgery, potentially improving outcomes.
What could go wrong: This is a single-center Phase 4 trial that has not yet started recruiting. The approach is experimental and may not improve patient outcomes or be generalizable to other centers.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

end stage renal failure

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

FLUID MANAGEMENT KIDNEY TRANSPLANT

Contacts and locations

Locations

Cedars Sinai Medical Center

Los Angeles, California, 90048, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.