Smart drug matching during kidney transplant could boost success

NCT ID NCT07633600

First seen Jun 11, 2026 · Last updated Jun 24, 2026 · Updated 3 times

Summary

This study tests whether giving specific blood pressure drugs based on a patient's circulation type during kidney transplant surgery improves how the body responds to fluids. Researchers will monitor 255 adults and assign drugs like vasopressin or norepinephrine based on real-time heart and blood vessel measurements. The goal is to see if this personalized approach leads to better blood pressure control and fluid management during the operation.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Cedars Sinai Medical Center

    Los Angeles, California, 90048, United States

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Vasopressin, Norepinephrine, Calcium Chloride, Dopamine

What this could lead to

If successful, this could lead to better blood pressure and fluid management during kidney transplant surgery, potentially improving outcomes.

What could go wrong

This is a single-center Phase 4 trial that has not yet started recruiting. The approach is experimental and may not improve patient outcomes or be generalizable to other centers.

Conditions

The condition(s) this trial relates to.

end stage renal failure

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.