Can DNA predict transplant trouble in kids?
NCT ID NCT07194057
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 2 times
Summary
This study will analyze the DNA and chemical marks on DNA of 200 children who have had a liver or kidney transplant. Researchers want to find genetic clues that might explain why some children develop serious complications like organ rejection, infections, or cancer after transplant. No extra procedures are needed—samples are taken during routine care. The goal is to better predict and manage these risks.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Whole genome sequencing and methylation analysis
What this could lead to
If successful, this could help doctors predict and prevent complications after a child's organ transplant, improving long-term outcomes.
What could go wrong
This is an observational study, not a treatment trial. It is small (200 children) and early, so findings may not apply to all transplant patients.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Hospital Universitario La Paz
Madrid, Madrid, 28046, Spain
Contact Email: •••••@•••••
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Mediterranean Institute for Transplantation (ISMETT)
Palermo, Sicily, 90127, Italy
Contact Phone: •••-•••-•••• Email: •••••@•••••
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University Hospital Padova
Padova, 35128, Italy
Contact Phone: •••-•••-•••• Email: •••••@•••••
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University Medical Center Hamburg-Eppendorf (UKE),
Hamburg, 20251, Germany
Contact Phone: •••-•••-•••• Email: •••••@•••••