Instituto De Investigación Hospital Universitario La Paz

This trial tests whether colchicine, an anti-inflammatory drug used for gout, can reduce inflammation in the coronary arteries of people with HIV who have high cardiovascular risk. Participants take either colchicine or a placebo daily for 96 weeks, and changes in artery inflamma…

This early-stage trial is testing a type of immunotherapy called CAR T cells in children, adolescents, and young adults with acute lymphoblastic leukemia that has come back or not responded to standard treatments. The therapy involves taking the patient's own immune cells or dono…

This study tests whether checking a patient's genes before a kidney transplant can help doctors choose the best starting dose of the anti-rejection drug tacrolimus. About 114 adults on the transplant waiting list will be randomly assigned to either standard dosing or a dose based…

This study tests whether giving sedation as a gas (isoflurane) instead of through an IV (propofol) helps critically ill patients on breathing machines recover faster. About 620 adults in the ICU who need deep sedation will be randomly assigned to one of the two methods. The main …