Could a common gout pill protect hearts in HIV?
NCT ID NCT07704164
First seen Jul 15, 2026 · Last updated Jul 16, 2026 · Updated 1 time
Summary
This trial tests whether colchicine, an anti-inflammatory drug used for gout, can reduce inflammation in the coronary arteries of people with HIV who have high cardiovascular risk. Participants take either colchicine or a placebo daily for 96 weeks, and changes in artery inflammation are measured with a CT scan. The goal is to see if this approach could lower the risk of heart disease in this population.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- colchicine 0.5 mg tablet taken once daily
- What this could lead to
- If it works, this could point toward a way to lower heart attack risk in people with HIV by reducing artery inflammation.
- What could go wrong
- This is a small, early-phase trial (90 people) testing a surrogate marker, not heart attacks directly. Colchicine can cause gastrointestinal side effects and may not reduce inflammation enough to matter.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Fundación Jiménez Díaz
NOT_YET_RECRUITINGMadrid, Spain
Contact
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Hospital La Paz
RECRUITINGMadrid, 28046, Spain
Contact
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Hospital Universitario Vall d' Hebron
RECRUITINGBarcelona, Spain
Contact
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Hospital Universitario de la Princesa
NOT_YET_RECRUITINGMadrid, Spain
Contact
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