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Gene test before kidney transplant could prevent drug dosing errors

NCT ID NCT06701825

Recruiting now Disease control Sponsor: Instituto de Investigación Hospital Universitario La Paz Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study tests whether checking a patient's genes before a kidney transplant can help doctors choose the best starting dose of the anti-rejection drug tacrolimus. About 114 adults on the transplant waiting list will be randomly assigned to either standard dosing or a dose based on their genetic profile. The goal is to see if the genetic approach helps patients reach the ideal drug level faster, which could lower the risk of rejection and reduce side effects.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Tacrolimus
What this could lead to
If successful, this approach could help kidney transplant patients reach the right drug levels faster, reducing rejection risk and side effects.
What could go wrong
This is a relatively small, early-phase trial (114 people) focused on drug dosing, not a new treatment. The benefit may be modest and may not apply to all patients or healthcare systems.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

chronic kidney disease chronic renal failure syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

IMMUNOSUPPRESSION KIDNEY DISEASE, CHRONIC TRANSPLANT RECIPIENT (KIDNEY)

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Hospital La Paz

    RECRUITING

    Madrid, Madrid, 28046, Spain

    Contact

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