LIVER TRANSPLANT
Clinical trials for LIVER TRANSPLANT explained in plain language.
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Could a vaccine before liver transplant cut antiviral use?
⭐️ VACCINE ⭐️ Recruiting nowThis phase 2 trial tests a CMV vaccine (CMV-MVA Triplex) given before a liver transplant to see if it reduces the need for antiviral drugs after surgery. The study enrolls 416 CMV-negative adults awaiting a liver transplant from a CMV-positive donor. Participants receive two vacc…
Matched conditions: LIVER TRANSPLANT
Phase: PHASE2 • Sponsor: National Institute of Allergy and Infectious Diseases (NIAID) • Aim: ⭐️ VACCINE ⭐️
Last updated Jun 27, 2026 12:03 UTC
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Liver transplant kids test cutting meds in half
Disease control Recruiting nowThis study looks at whether children who received a liver transplant before age 7 can safely cut their anti-rejection drugs by 50%. One hundred kids will slowly reduce their medication over 18 months, with frequent blood tests and liver biopsies to check for rejection. The goal i…
Matched conditions: LIVER TRANSPLANT
Phase: PHASE2 • Sponsor: National Institute of Allergy and Infectious Diseases (NIAID) • Aim: Disease control
Last updated Jun 27, 2026 13:04 UTC
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Could a single pill replace a cocktail of Anti-Rejection drugs after liver transplant?
Disease control Recruiting nowThis study tests whether liver transplant patients can safely switch from a standard anti-rejection drug (tacrolimus) to a different drug (everolimus) to protect their kidneys. About 340 adults who received their first liver transplant will be followed for 18-20 months. The goal …
Matched conditions: LIVER TRANSPLANT
Phase: PHASE2 • Sponsor: National Institute of Allergy and Infectious Diseases (NIAID) • Aim: Disease control
Last updated Jun 27, 2026 12:37 UTC
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Could a drug combo free liver transplant patients from daily anti-rejection pills?
Disease control Recruiting nowThis early-stage study tests whether switching from the standard anti-rejection drug tacrolimus to everolimus plus epoetin can safely allow liver transplant recipients to stop all immunosuppressants. Twenty stable adult patients who received a liver transplant 1–10 years ago will…
Matched conditions: LIVER TRANSPLANT
Phase: PHASE1 • Sponsor: National Institute of Allergy and Infectious Diseases (NIAID) • Aim: Disease control
Last updated Jun 27, 2026 12:04 UTC
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New hope for liver transplant patients with recurrent cancer: immunotherapy combo under study
Disease control Recruiting nowThis phase 2 trial is testing whether a combination of two drugs, atezolizumab and bevacizumab, can safely treat liver cancer that has come back after a liver transplant. The study includes 50 patients who will receive the drug combo every three weeks along with a strict immunosu…
Matched conditions: LIVER TRANSPLANT
Phase: PHASE2 • Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Disease control
Last updated Jun 27, 2026 11:00 UTC
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Can apps keep transplant patients healthy? new study tests digital lifestyle coaching
Disease control Recruiting nowThis study tests whether a doctor-led counseling program, combined with two smartphone apps (Nutrida and Gamebus), can help older adults (60+) who have had a liver or kidney transplant eat better and be more active. Sixty participants will first receive lifestyle advice, then use…
Matched conditions: LIVER TRANSPLANT
Phase: NA • Sponsor: IRCCS Azienda Ospedaliero-Universitaria di Bologna • Aim: Disease control
Last updated Jun 27, 2026 08:06 UTC
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New hope for liver cancer return after transplant: drug trial launches
Disease control Recruiting nowThis study tests a drug called cabozantinib in 20 adults whose liver cancer returned after a liver transplant. The goal is to see if the drug can control the cancer. Participants take the drug until it stops working or side effects become too bothersome.
Matched conditions: LIVER TRANSPLANT
Phase: PHASE2 • Sponsor: University Health Network, Toronto • Aim: Disease control
Last updated Jun 27, 2026 08:01 UTC
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Machine breathes new life into fatty livers for transplant
Disease control Recruiting nowThis trial tests whether a machine called Normothermic Machine Perfusion (NMP) can revive moderately fatty donor livers so they can be safely transplanted. Researchers will place livers with 30-60% fat on the machine, check their quality, and transplant those that meet safety cri…
Matched conditions: LIVER TRANSPLANT
Phase: NA • Sponsor: Massachusetts General Hospital • Aim: Disease control
Last updated Jun 27, 2026 07:56 UTC
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Pre-Surgery carb drink may speed liver transplant recovery
Symptom relief Recruiting nowThis study tests if drinking a carbohydrate beverage before liver transplant surgery helps patients recover more quickly and spend fewer days in the hospital. About 434 adults receiving a liver transplant will be randomly assigned to drink either the carbohydrate drink or a place…
Matched conditions: LIVER TRANSPLANT
Phase: NA • Sponsor: Medical University of Warsaw • Aim: Symptom relief
Last updated Jun 27, 2026 13:00 UTC
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New study aims to catch transplant complications early with blood and urine tests
Knowledge-focused Recruiting nowThis study is looking at 1,000 liver transplant recipients to see if testing their blood, urine, and tissue samples can detect early signs of chronic kidney disease, acute rejection, or hepatitis C. The goal is to find simple biomarkers that could lead to earlier treatment and fe…
Matched conditions: LIVER TRANSPLANT
Sponsor: Northwestern University • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:36 UTC
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New app aims to ease tough transition for young liver transplant patients
Knowledge-focused Recruiting nowThis study is creating a digital tool to help teenagers and young adults (ages 14-20) who have had or are waiting for a liver transplant as they move from pediatric to adult care. The tool helps patients and doctors track medication use and well-being from home, reducing hospital…
Matched conditions: LIVER TRANSPLANT
Sponsor: FROM- Fondazione per la Ricerca Ospedale di Bergamo- ETS • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:09 UTC
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Study investigates hidden health risks for children of transplant mothers
Knowledge-focused Recruiting nowThis study looks at the long-term health of children (16 years and older) whose mothers had a solid organ transplant before pregnancy. Researchers want to see if these children have higher risks for heart or kidney problems, possibly due to the mother's transplant or medications.…
Matched conditions: LIVER TRANSPLANT
Sponsor: University Medical Center Groningen • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:05 UTC
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Sugar sensors after transplant: a closer look at recovery
Knowledge-focused Recruiting nowThis study follows 40 liver transplant patients after they leave the hospital, using a continuous glucose monitor to track their blood sugar levels. The goal is to see how blood sugar control relates to complications like wound healing or other transplant outcomes. Participants m…
Matched conditions: LIVER TRANSPLANT
Sponsor: Icahn School of Medicine at Mount Sinai • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:57 UTC