Could a drug combo free liver transplant patients from daily anti-rejection pills?

NCT ID NCT06832189

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This early-stage study tests whether switching from the standard anti-rejection drug tacrolimus to everolimus plus epoetin can safely allow liver transplant recipients to stop all immunosuppressants. Twenty stable adult patients who received a liver transplant 1–10 years ago will take part. The main goal is to see if this approach is safe and can lead to 'operational tolerance'—where the body accepts the new liver without needing lifelong medication.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Northwestern University Feinberg School of Medicine

    RECRUITING

    Chicago, Illinois, 60611, United States

  • University of California San Francisco School of Medicine

    RECRUITING

    San Francisco, California, 94143, United States

  • University of Pennsylvania Medical Center

    RECRUITING

    Philadelphia, Pennsylvania, 19104, United States

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