INGUINAL HERNIA

This study looks at how well a new robotic system (Medtronic Hugo™) works for fixing inguinal and ventral hernias. About 206 adults will have robotic hernia repair, and researchers will track if the surgery is completed without switching to another method and if any complications…

This study looks at a special mesh called 4DMESH® used in laparoscopic hernia repair. The goal is to see if it helps prevent hernias from coming back and reduces pain over 5 years. About 196 adults with a first-time inguinal or femoral hernia will take part. Researchers will trac…

This study is testing a new mesh called Swing-Mesh™ for fixing groin hernias. The mesh is designed to stay in place without stitches or glue. About 300 adults having planned hernia surgery will get this mesh. Researchers will check for hernia return, pain, and other problems over…

This study tests a glue device called LiquiBand FIX8 to hold hernia mesh in place during open surgery. About 109 people with a first-time inguinal hernia will get the glue, and doctors will check if it works well and causes few side effects over 12 months. The goal is to see if t…

This study compares two ways of placing a 3D mesh patch during inguinal hernia repair: fixing it with a single stitch versus not fixing it at all. The goal is to see which approach causes less chronic pain and fewer hernia recurrences. About 150 adults with a specific type of her…

This phase 4 trial compares giving no opioids versus a small prescription of 5 opioid tablets after inguinal hernia repair. About 904 adults having elective surgery will be randomly assigned to either group. The main goal is to see if the no-opioid group requests fewer refills wh…

This study tests whether a longer-lasting pain blocker (Exparel) works better than the standard one (Marcaine) for pain control after hernia repair. About 200 adults having minimally invasive hernia surgery will receive one of the two drugs via a nerve block before surgery. Resea…

This study looks at how spinal anesthesia and the drug clonidine affect tiny nerve fibers (A-delta fibers) in people having hernia surgery. Researchers will measure nerve signals before, during, and after anesthesia to see if adding clonidine changes how the nerves work. The goal…

This study follows 801 infants who had surgery for pyloric stenosis. Some have a small opening in the groin (patent processus vaginalis). Researchers will track them until age 18 to see how many develop an inguinal hernia and when. The goal is to understand the natural history of…

This study looks at what to do when a surgeon finds a small, hidden groin hernia during a routine hernia repair. It compares fixing it right away versus just watching it over time. The goal is to help patients and doctors decide the best approach by creating a simple decision-mak…