Could a muscle relaxant cut opioid use after hernia surgery?

NCT ID NCT05388929

Ongoing Symptom relief Sponsor: Prisma Health-Upstate Source: ClinicalTrials.gov ↗

First seen Jul 10, 2026 · Last updated Jul 10, 2026

Summary

This study tests whether adding methocarbamol, a muscle relaxant, to standard pain relief can reduce the need for opioids after ventral or inguinal hernia repair. Adults undergoing surgery are randomly assigned to receive either standard opioids, methocarbamol alone, or both. The study tracks how many people need extra opioid prescriptions and their total opioid use over 30 days after surgery.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Methocarbamol
What this could lead to: If it works, this could point toward a way to reduce opioid use after hernia surgery, lowering the risk of addiction and side effects.
What could go wrong: This is a small pilot study, so results may not be conclusive. Methocarbamol may not reduce pain or opioid needs, and could cause side effects like drowsiness.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for INGUINAL HERNIA are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

Hernia, Inguinal Hernia, Ventral

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

INGUINAL HERNIA VENTRAL HERNIA

Contacts and locations

Show contact details

Locations

Prisma Health

Greenville, South Carolina, 29615, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.