Spinal anesthesia study probes nerve fiber changes
NCT ID NCT03121261
First seen Jun 27, 2026 ยท Last updated Jun 27, 2026
Summary
This study looks at how spinal anesthesia and the drug clonidine affect tiny nerve fibers (A-delta fibers) in people having hernia surgery. Researchers will measure nerve signals before, during, and after anesthesia to see if adding clonidine changes how the nerves work. The goal is to better understand how these drugs interact with the nervous system, not to treat a disease.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Phase 4
Runs after approval, following long-term safety and how well the treatment works in everyday use.
- Participants
-
About 60 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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May 2017
- Expected to finish
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Oct 2028
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 60 years
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: ASA one and two status BMI 18,5 to 24 Exclusion Criteria: Coagulation disorders Polyneuropathy Diabetes mellitus Alcoholism Systemic inflammatory and malignant diseases Stroke
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Clinical Hospital Dubrava
Zagreb, 10000, Croatia
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Can a common steroid stretch spinal anesthesia and keep surgery patients comfortable longer?
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- Can pressing these points cut Post-Surgery pain?
- Can a slower oxytocin infusion prevent dangerous blood pressure drops in C-Sections?
- Which spinal anesthetic gets you back on your feet sooner?
- Can ultrasound make spinal anesthesia safer for the elderly?