Simple steroid shot before C-Section could cut Post-Op pain and opioid use

NCT ID NCT07718360

First seen Jul 21, 2026 · Last updated Jul 22, 2026 · Updated 1 time

Summary

This study investigates whether giving a single intravenous dose of the steroid dexamethasone before a planned cesarean section can reduce pain after the operation. Eighty women undergoing a scheduled C-section under spinal anesthesia are randomly assigned to receive either dexamethasone or a placebo (salt water). Pain levels are measured on a 0-10 scale at several time points after surgery, and the need for additional pain relief is tracked. The goal is to see if this simple, low-cost intervention can improve recovery and reduce reliance on other painkillers.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
a single intravenous dose of dexamethasone (8 mg), a steroid medicine
What this could lead to
If effective, this simple, low-cost approach could become a standard way to improve pain control after cesarean sections, reducing the need for opioid painkillers.
What could go wrong
This is a small, single-center study with 80 participants. Results may not apply to all patients or settings, and the long-term effects of a single steroid dose in this context are not fully explored.

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Conditions

The condition(s) this trial relates to.

Pain, Postoperative

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • KRL Hospital, Islamabad

    Islamabad, Federal Capital Territory, 44000, Pakistan

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