HIP FRACTURES

This study follows 368 adults who need a partial hip replacement (hemiarthroplasty) using Corin devices. It aims to check how safe and effective the implants are over 10 years, focusing on complications and mobility. Participants have conditions like hip fractures, arthritis, or …

This study looks at whether doing hip fracture surgery sooner (within hours) can lower the chance of death within 90 days for patients who also have a recent heart injury. About 1100 adults aged 45 and older with a hip fracture and elevated troponin (a sign of heart damage) will …

This study compares two surgeries for unstable hip fractures in adults 65 and older: the standard intramedullary nail versus hip replacement. The goal is to see which approach leads to better mobility, quality of life, and fewer repeat surgeries. About 170 participants will be fo…

This study looks for a hidden spine condition called cervical myelopathy in people who broke a hip from a simple fall. Researchers will check 75 patients with a history, physical exam, and MRI if needed. The goal is to find and treat this condition early to help prevent more fall…

This study tests a procedure called LOEP that strengthens the hip bone to prevent a second fracture in women over 65 who have already broken one hip. About 2400 women will be randomly assigned to receive the procedure or standard care, and they will be followed for at least 5 yea…

This study looks at whether giving two doses of tranexamic acid, instead of one, can safely reduce blood loss and the need for blood transfusions in older adults (65+) having surgery for certain hip fractures. Participants will receive either one dose before surgery or two doses …

This study compares standard pain management to a special nerve block (PENG block) in 70 adults aged 30-85 having hip fracture surgery. The goal is to see if the block reduces pain, cuts the need for extra painkillers, and helps patients get up and walk sooner. Researchers will a…

This study tests whether remimazolam, a newer anesthetic, causes less confusion (delirium) after hip or knee surgery in older adults compared to the standard drug propofol. About 82 elderly patients will receive one of the two drugs during surgery. Researchers will check for conf…

This study compares two types of nerve blocks (PENG vs femoral) to see which provides better pain relief for people with hip fractures. About 352 adults with hip fractures will receive one of the two blocks based on the month they arrive. Researchers will measure pain scores befo…

This study tests whether giving a combination of two medicines (esketamine and dexmedetomidine) during hip fracture surgery can improve sleep quality afterward in patients aged 65 and older. Half of the 96 participants will receive the drug combo, and the other half will receive …

This study tests if freezing a specific nerve group (cryoablation) provides better pain control 30 days after hip fracture surgery compared to the standard method (a catheter that delivers numbing medicine). About 150 adults aged 18-85 having hip fracture repair will take part. T…

This study tests whether a long-acting numbing drug (liposomal bupivacaine) plus a standard numbing medicine works better than the usual numbing medicine (ropivacaine) for pain after hip replacement. About 60 adults with hip fractures or hip damage will receive one of the two tre…

This study compares a new local numbing method (PENG block) to standard spinal anesthesia for adults having hip replacement after a fracture. The goal is to see if the new technique controls pain just as well while allowing earlier leg movement and causing less nausea. About 100 …

This study looks at whether a mobile app can help people do simple exercises while still in bed after hip, knee, or spine surgery. About 100 adults will use the app to guide their recovery, and researchers will measure how well they regain movement and how satisfied they are with…

This study tests a simple conversation aid that doctors can use at the bedside to help patients aged 50 and older discuss anesthesia options before hip fracture surgery. The goal is to see if this tool improves shared decision-making and communication. About 1,881 participants ac…

This study collects bone marrow samples from 24 adults aged 65 and older during hip surgery. Researchers will analyze the cells' metabolism and look for specific genetic changes linked to clonal hematopoiesis (CHIP). The goal is to understand how these changes affect stem cell fu…

This study compares a new surgical implant (three screws locked together by a plate) with standard screws for fixing hip fractures in adults aged 18-64. The goal is to see which method keeps the broken bone more stable during healing. Researchers will track 75 participants for on…

This study looks at whether spinal anesthesia or general anesthesia leads to fewer lung problems after hip surgery in older adults. It involves 40 people aged 65 and older who have waited more than 48 hours for surgery. Researchers will measure oxygen levels and lung function to …