Race against time: can speedy hip surgery save more lives?

NCT ID NCT04743765

Recruiting now Disease control Sponsor: Population Health Research Institute Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looks at whether doing hip fracture surgery within 6 hours, instead of waiting longer, can reduce deaths in patients who also have a recent heart injury. About 1100 adults aged 45 and older with a hip fracture and elevated troponin (a sign of heart damage) will be randomly assigned to either accelerated surgery or standard care. The main goal is to see if faster treatment lowers the chance of dying within 90 days.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: accelerated medical clearance and surgery
What this could lead to: If it works, this could show that faster surgery after a hip fracture lowers the risk of death for patients who also have a heart injury.
What could go wrong: This is a mid-stage trial, so results are not yet proven. The benefit may be small or not apply to all patients, and rushing surgery could increase risks.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

hip fracture

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

HIP FRACTURES MYOCARDIAL INJURY

Contacts and locations

Locations

Aga Khan University
RECRUITING

Karachi, Sindh, 74800, Pakistan
All India Institute of Medical Sciences (AIIMS)
RECRUITING

New Delhi, National Capital Territory of Delhi, 110029, India
B and B Hospital
RECRUITING

Lalitpur, Bagmati, 44700, Nepal
Bangalore Baptist Hospital
RECRUITING

Bangalore, Karnataka, 560024, India
Bryan Medical Center
RECRUITING

Lincoln, Nebraska, 68506, United States
CISSS de Laval
RECRUITING

Laval, Quebec, H7M 3L9, Canada
Chandler Regional Medical Center
RECRUITING

Chandler, Arizona, 85224, United States
Christus Muguerza del Parque
RECRUITING

Chihuahua City, Chihuahua, 31000, Mexico
Cleveland Clinic
RECRUITING

Cleveland, Ohio, 44195, United States
Clinica Santa Maria
RECRUITING

Santiago, 7520378, Chile
Cliniques Universitaires Saint Luc - University Catholic of Louvain
RECRUITING

Woluwe-Saint-Lambert, Brussels Capital, 1200, Belgium
Combined Military Hospital
RECRUITING

Rawalpindi, Punjab Province, 46000, Pakistan
Cruz Verde Guadalajara
RECRUITING

Guadalajara, Jalisco, 44410, Mexico
Dartmouth-Hitchcock Medical Center
RECRUITING

Lebanon, New Hampshire, 03756, United States
Deventer Hospital
RECRUITING

Deventer, Overijssel, 7416 SE, Netherlands
Emory University at Grady Memorial Hospital
RECRUITING

Atlanta, Georgia, 30322, United States
Galliera Hospital
RECRUITING

Genova, 16128, Italy
Ghurki Trust Teaching Hospital
RECRUITING

Lahore, Punjab Province, 54000, Pakistan
Government Medical College
RECRUITING

Trivandrum, Kerala, 695011, India
Government TD Medical College
RECRUITING

Alappuzha, Kerala, 688005, India
Groote Schuur Hospital
RECRUITING

Cape Town, Western Cape, 7925, South Africa
Hayat Abad Medical Complex
RECRUITING

Peshawar, KPK, 25000, Pakistan
Hospital Clinic of Barcelona
RECRUITING

Barcelona, Barcelona, 08036, Spain
Hospital Clinico Universitario de Vallad
RECRUITING

Valladolid, Valladolid, 47007, Spain
Hospital Costa del Sol
RECRUITING

Marbella, Malaga, 29603, Spain
Hospital Sant Camil
RECRUITING

Sant Pere de Ribes, Barcelona, 08810, Spain
Hospital Universitari Parc Tauli
RECRUITING

Sabadell, Barcelona, 08208, Spain
Hospital Universitari Sagrat Cor
RECRUITING

Barcelona, Barcelona, 08029, Spain
Hospital Universitari Vall d'Hebron
RECRUITING

Barcelona, Barcelona, 08035, Spain
Hospital Universitario Mutua de Terrassa
RECRUITING

Terrassa, Barcelona, 08221, Spain
Hospital de la Santa Creu I Sant Pau
RECRUITING

Barcelona, Barcelona, 08041, Spain
Hospital of Perugia
RECRUITING

Perugia, Umbria, 06129, Italy
Indus Hospital & Health Network
RECRUITING

Karachi, Sindh, Pakistan
JIPMER
RECRUITING

Puducherry, Puducherry, 605006, India
Juravinski Hospital
RECRUITING

Hamilton, Ontario, L8V 1C3, Canada
King Faisal Specialist Hospital
RECRUITING

Riyadh, Riyadh Region, 11211, Saudi Arabia
Lahey Hospital and Medical Center
RECRUITING

Burlington, Massachusetts, 01805, United States
Markham Stouffville Hospital
RECRUITING

Markham, Ontario, L3P 7P3, Canada
Maroof International Hospital
RECRUITING

Islamabad, ICT, 44000, Pakistan
Mayo Clinic
RECRUITING

Rochester, Minnesota, 55905, United States
Montefiore Medical Center
RECRUITING

The Bronx, New York, 10467, United States
Oregon Health and Science University
RECRUITING

Portland, Oregon, 97239, United States
Ospedale Galeazzi SpA
RECRUITING

Milan, 20157, Italy
Ospedale San Raffaele S.r.l.
RECRUITING

Milan, 20132, Italy
Ottawa General Hospital
RECRUITING

Ottawa, Ontario, K1H 8L6, Canada
Parc Sanitari Sant Joan de Déu
RECRUITING

Barcelona, 08830, Spain
Pontifica Universidad Catolica de Chile
RECRUITING

Santiago, RM, 83300024, Chile
Queen Mary Hospital
RECRUITING

Hong Kong, Hong Kong
SPZOZ Myslenice
RECRUITING

Myślenice, Malopolska, 32-400, Poland
Shifa International Hospitals Ltd.
RECRUITING

Islamabad, ICT, 44000, Pakistan
Sinai Hospital of Baltimore
RECRUITING

Baltimore, Maryland, 21215, United States
South Karelia Central Hospital
RECRUITING

Lappeenranta, 53130, Finland
St. Joseph's Healthcare Hamilton
RECRUITING

Hamilton, Ontario, L8N 4A6, Canada
St. Luke's University Health Network
RECRUITING

Bethlehem, Pennsylvania, 18015, United States
Stellenbosch University - Tygerberg Hospital
RECRUITING

Cape Town, Western Cape, 7505, South Africa
Stichting OLVG
RECRUITING

Amsterdam, Netherlands
Tampere University Hospital
RECRUITING

Tampere, 33521, Finland
The John Hunter Hospital
RECRUITING

New Lambton Heights, New South Wales, 2305, Australia
The Regents of the University of California
RECRUITING

Davis, California, 95618, United States
The University of Texas Health Science Center at Houston
RECRUITING

Houston, Texas, 77030, United States
Tufts Medical Center
RECRUITING

Boston, Massachusetts, 02111, United States
University Medical Center of Southern Nevada
RECRUITING

Las Vegas, Nevada, 89102, United States
University of Alberta Hospital
RECRUITING

Edmonton, Alberta, T6G 2B7, Canada
University of Malaya Medical Centre
RECRUITING

Kuala Lumpur, 59100, Malaysia
University of Maryland
RECRUITING

Baltimore, Maryland, 20742, United States
University of Michigan
RECRUITING

Ann Arbor, Michigan, 48109, United States
University of São Paulo
RECRUITING

São Paulo, São Paulo, 05403010, Brazil
University of Wisconsin
RECRUITING

Madison, Wisconsin, 53715, United States
Victoria Hospital
RECRUITING

London, Ontario, N6A 5W9, Canada
Yale New Haven Hospital
RECRUITING

New Haven, Connecticut, 06520, United States

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