HIDRADENITIS SUPPURATIVA (HS)

This study tests an oral drug called povorcitinib in 40 adolescents aged 12 to 17 with moderate to severe hidradenitis suppurativa (HS), a chronic skin condition causing painful boils and tunnels. Over 54 weeks, researchers will check the drug's safety, how the body processes it,…

This study offers continued treatment with povorcitinib for up to 600 adults with hidradenitis suppurativa who completed a prior trial and saw benefit. The main goal is to track side effects over time, with a secondary focus on reducing skin abscesses, nodules, and tunnels. Parti…

This study tests a drug called secukinumab in Chinese adults with moderate to severe hidradenitis suppurativa, a painful skin condition that causes boils and tunnels under the skin. The goal is to see if the drug reduces skin lesions and prevents flare-ups over 16 weeks. About 36…

This study tests a new drug called BFB759 for people with moderate to severe hidradenitis suppurativa (HS), a painful skin condition that causes boils and abscesses. About 210 adults will receive either BFB759 or a placebo to see if the drug reduces the number of painful bumps an…

This study tests whether high-dose radiotherapy can improve symptoms of hidradenitis suppurativa, a painful skin condition. Ten adults with moderate to severe disease will receive radiation to one armpit while the other armpit gets standard care. Researchers will compare changes …

This study tests an experimental drug called SCT650C in 60 adults with moderate to severe hidradenitis suppurativa (HS), a painful skin condition causing boils and tunnels. The goal is to see if the drug can reduce abscesses and inflammation by at least 75% after 16 weeks. Partic…

This study tests whether NAV-240, given as an IV infusion, works better than a placebo for adults with moderate-to-severe hidradenitis suppurativa (HS). HS causes painful, inflamed bumps and tunnels under the skin. The main goal is to see if NAV-240 can reduce these bumps by at l…

This program provides access to secukinumab (AIN457) for people with hidradenitis suppurativa who have no other treatment options. It is for patients with serious disease who cannot join a clinical trial or have exhausted all available therapies. Doctors must request access on be…

This study compares a new wound dressing, Pelashield PainGuard, to the standard Restrata dressing for people with severe hidradenitis suppurativa (HS) who need surgery. The new dressing contains silver to fight bacteria and lidocaine to numb pain. Researchers will track healing t…

This study tests whether a new drug called CIT-013 can reduce symptoms of hidradenitis suppurativa, a chronic skin condition causing painful lumps. About 96 adults with moderate to severe HS will receive either 50 mg, 100 mg, or a placebo every two weeks for 12 weeks. Researchers…

This study tests a medicated foam (roflumilast) applied to the skin for hidradenitis suppurativa, a condition causing painful bumps and abscesses. About 20 adults with mild to moderate HS will use the foam for 16 weeks. The goal is to see if it reduces the number of inflamed nodu…

This study surveys 77 adults with moderate to severe hidradenitis suppurativa (HS) in Saudi Arabia who are starting the medication Cosentyx (secukinumab). Researchers will ask patients about their treatment satisfaction and quality of life after 24 weeks. The goal is to understan…

This pilot study tests a 1726-nm laser (AviClear) to reduce painful lumps and abscesses in hidradenitis suppurativa (HS), a chronic skin condition. Thirty adults with mild-to-moderate HS will have one side of their body treated with the laser and the other side with a sham proced…

This international study observes how people with hidradenitis suppurativa (a chronic skin condition) access healthcare, what treatments they receive, and how the disease affects their quality of life. Researchers collect data from routine medical records across multiple countrie…

This study monitors 36 people who previously received an experimental gene-modified regulatory T cell (Treg) therapy for rheumatoid arthritis or hidradenitis suppurativa. The goal is to check for any delayed side effects and see how long the modified cells last in the body. Parti…