HIDRADENITIS SUPPURATIVA (HS)
Clinical trials for HIDRADENITIS SUPPURATIVA (HS) explained in plain language.
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Can a new injection tame the painful lumps of hidradenitis suppurativa?
Disease control Not yet recruitingThis phase 2 trial tests whether an investigational medicine called SPY072 can improve hidradenitis suppurativa (HS), a chronic skin condition causing painful lumps and tunnels. About 150 adults with moderate-to-severe HS who are already receiving standard care will be randomly a…
Matched conditions: HIDRADENITIS SUPPURATIVA (HS)
Phase: PHASE2 • Sponsor: Spyre Therapeutics, Inc. • Aim: Disease control
Last updated Aug 16, 2026 00:00 UTC
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Could botox calm the painful skin flares of hidradenitis suppurativa?
Disease control Not yet recruitingThis phase 2 trial tests whether injecting botulinum toxin (Botox) into skin affected by hidradenitis suppurativa (HS) can reduce the number of painful abscesses, nodules, and draining tunnels, and ease pain. About 40 people with HS will receive either Botox or a saline placebo i…
Matched conditions: HIDRADENITIS SUPPURATIVA (HS)
Phase: PHASE2 • Sponsor: University of Massachusetts, Worcester • Aim: Disease control
Last updated Aug 12, 2026 00:00 UTC
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Foam could ease painful skin lumps in hidradenitis suppurativa
Disease control Not yet recruitingThis study tests a medicated foam called roflumilast applied daily to hidradenitis suppurativa (HS) lesions for 16 weeks. It includes adolescents and adults with mild to moderate HS (Hurley stage I or II) who have 4 to 10 painful lumps or abscesses but no draining tunnels. The ma…
Matched conditions: HIDRADENITIS SUPPURATIVA (HS)
Phase: PHASE2 • Sponsor: Harrison Dermatology • Aim: Disease control
Last updated Jul 11, 2026 00:00 UTC
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Poop pills for painful skin? fecal transplant trial targets hidradenitis
Disease control Not yet recruitingThis pilot study tests whether fecal microbiota transplantation (FMT) can improve moderate to severe hidradenitis suppurativa (HS), a painful skin condition. Researchers will give 24 adults a single FMT and track changes in their skin lesions over 12 weeks. The goal is to see if …
Matched conditions: HIDRADENITIS SUPPURATIVA (HS)
Phase: PHASE1 • Sponsor: University Hospital, Clermont-Ferrand • Aim: Disease control
Last updated Jun 27, 2026 14:03 UTC
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New combo therapy aims to tame painful skin condition
Disease control Not yet recruitingThis study tests whether combining an anti-IL-17A/F antibody (bimekizumab) with a non-ablative fractional laser can safely reduce symptoms of mild to moderate hidradenitis suppurativa, a chronic skin condition causing painful lumps. Fifty adults will receive the combination every…
Matched conditions: HIDRADENITIS SUPPURATIVA (HS)
Phase: PHASE4 • Sponsor: Second Affiliated Hospital, School of Medicine, Zhejiang University • Aim: Disease control
Last updated Jun 27, 2026 12:24 UTC
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New study tests local injections for stubborn HS lesions
Disease control Not yet recruitingThis study compares injecting secukinumab directly into skin lesions versus standard under-the-skin injections for people with localized hidradenitis suppurativa (HS). The goal is to see if local delivery works better and causes fewer side effects. Thirty adults with HS lesions i…
Matched conditions: HIDRADENITIS SUPPURATIVA (HS)
Phase: PHASE4 • Sponsor: Peking Union Medical College • Aim: Disease control
Last updated Jun 27, 2026 08:01 UTC
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Laser showdown: can a newer laser match the standard for HS?
Symptom relief Not yet recruitingThis study tests whether alexandrite laser works as well as Nd:YAG laser for treating hidradenitis suppurativa (HS), a painful skin condition. Twenty-one people will receive both lasers on different sides of their body to compare results. The goal is to see if alexandrite can red…
Matched conditions: HIDRADENITIS SUPPURATIVA (HS)
Phase: NA • Sponsor: Geisinger Clinic • Aim: Symptom relief
Last updated Jun 27, 2026 12:24 UTC
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Immune cell clues may unlock better HS treatment
Knowledge-focused Not yet recruitingThis study looks at how certain immune cells, called MAIT cells, behave in people with hidradenitis suppurativa (HS), a painful skin condition. Researchers will take skin and blood samples from 45 adults with HS and compare them to samples from people with other skin diseases. Th…
Matched conditions: HIDRADENITIS SUPPURATIVA (HS)
Phase: NA • Sponsor: Hospices Civils de Lyon • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:02 UTC
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New study to measure hidden toll of painful skin condition
Knowledge-focused Not yet recruitingThis study will follow 100 Canadian adults with hidradenitis suppurativa (HS), a painful skin condition, to measure how it affects their work and daily life. Participants will fill out questionnaires about work productivity and quality of life. No treatment is given—the goal is t…
Matched conditions: HIDRADENITIS SUPPURATIVA (HS)
Sponsor: PeriPharm • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:08 UTC