HEPATITIS C

This study tested a combination of two oral drugs, bemnifosbuvir and ruzasvir, in 275 adults with chronic hepatitis C. The main goal was to see if the treatment could clear the virus from the blood 12 weeks after finishing therapy. The trial was open-label, meaning everyone knew …

This early-phase study tested a new drug called MP-424 combined with two standard hepatitis C medications (peginterferon alfa 2b and ribavirin) in 20 people with chronic genotype 1b hepatitis C. The main goal was to check the safety and how the drug moves through the body, not to…

This study tested whether livers from donors with hepatitis C could be safely given to people who did not have hepatitis C and needed a liver transplant. Five participants received such a liver and were then treated with an antiviral drug to prevent or cure any infection. The goa…

This study tested a new drug called MP-424 combined with two standard hepatitis C medicines (peginterferon alfa-2b and ribavirin) in 189 adults with genotype 1 hepatitis C who had never been treated before. The main goal was to see if the virus was still undetectable 24 weeks aft…

This phase 2 study tested the drug MP-424 in 15 adults with chronic hepatitis C (genotype 1b) who had not taken interferon before. The goal was to see if the drug could make the virus undetectable 24 weeks after treatment ended. The study also checked for side effects. Results he…

This study tested a new drug called MP-424 combined with two standard medicines (peginterferon alfa-2b and ribavirin) in 32 adults with genotype 1 hepatitis C who had not responded to earlier treatment. The main goal was to see if the virus could be cleared from the blood 24 week…

This study tested whether a GPS-based mobile app, financial incentives, and peer mentors could help men who have sex with men and transgender women leaving jail get HIV prevention services like PrEP and testing. 233 participants were split into two groups: one got routine case ma…

This study tested a program to help 219 incarcerated people with HIV, hepatitis C, or substance use disorder get health care after they leave prison. Participants worked with a nurse case manager before and after release to plan their care. The goal was to see if the program was …

This study looked at how common hepatitis B and C are in African and Asian immigrants living in Minnesota, and how these infections might lead to liver cancer. Researchers tested 892 adults for hepatitis markers and tracked liver cancer cases over time. The goal was to better und…

This study looked at 10 adults with chronic hepatitis C to find proteins attached to the virus particles. Researchers purified virus from blood samples and identified these proteins to learn how the virus infects cells and makes copies of itself. The goal was to discover new targ…

This study looked at whether women aged 50 to 74 getting a routine mammogram for breast cancer screening would also agree to a quick hepatitis C test. The goal was to find undiagnosed hepatitis C cases and connect those women to care. About 1,500 women took part, and the study me…

This study aimed to find out how many people held at the Nîmes administrative detention center have HIV, hepatitis B, or hepatitis C. Researchers used rapid tests to get results quickly, since many detainees leave before standard lab results come back. A total of 350 detainees to…

This study looked at 805 blood donors who tested positive for hepatitis C virus (HCV) to learn how the virus spreads, who gets sick, and what happens over time. Participants gave blood samples and answered questions about their health and lifestyle. The goal was to better underst…