HEART FAILURE WITH PRESERVED EJECTION FRACTION (HFPEF
Clinical trials for HEART FAILURE WITH PRESERVED EJECTION FRACTION (HFPEF explained in plain language.
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Weight-Loss drug mounjaro could keep hearts in rhythm after ablation
Disease control Not yet recruitingThis study tests whether the diabetes and weight-loss drug tirzepatide (Mounjaro) can reduce the chance of atrial fibrillation coming back after a heart procedure called catheter ablation. About 602 adults with obesity and a type of heart failure (HFpEF) will get either tirzepati…
Matched conditions: HEART FAILURE WITH PRESERVED EJECTION FRACTION (HFPEF
Phase: PHASE4 • Sponsor: Yunlong Wang • Aim: Disease control
Last updated Jun 27, 2026 13:02 UTC
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Could a gut bacteria transplant ease heart failure in seniors?
Disease control Not yet recruitingThis study tests whether transplanting healthy gut bacteria (fecal microbiota transplantation) can improve quality of life and exercise ability in elderly patients with a common type of heart failure (HFpEF). Fifty adults aged 60 and older will receive either the transplant or a …
Matched conditions: HEART FAILURE WITH PRESERVED EJECTION FRACTION (HFPEF
Phase: PHASE1, PHASE2 • Sponsor: The First Affiliated Hospital of Air Force Medicial University • Aim: Disease control
Last updated Jun 27, 2026 13:02 UTC
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Pacemaker upgrade could ease stiff heart failure
Disease control Not yet recruitingThis pilot study tests a special pacemaker-like device called Moderato Plus in 20 people with high blood pressure and a type of heart failure where the heart pumps normally but is too stiff (HFpEF). The device delivers Cardiac Neuromodulation Therapy to help control blood pressur…
Matched conditions: HEART FAILURE WITH PRESERVED EJECTION FRACTION (HFPEF
Phase: NA • Sponsor: BackBeat Medical Inc • Aim: Disease control
Last updated Jun 27, 2026 12:35 UTC
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Can quick drug optimization after heart failure hospitalization save lives in women?
Disease control Not yet recruitingThis study tests whether quickly starting and increasing guideline-recommended heart failure medications after hospitalization improves outcomes in women. About 360 women from 13 Italian hospitals will be randomly assigned to either a high-intensity care group (rapid drug optimiz…
Matched conditions: HEART FAILURE WITH PRESERVED EJECTION FRACTION (HFPEF
Phase: PHASE4 • Sponsor: IRCCS Policlinico S. Donato • Aim: Disease control
Last updated Jun 27, 2026 12:02 UTC
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AI eye on the heart: new tool spots rare amyloidosis earlier
Diagnosis Not yet recruitingThis study tests whether an artificial intelligence (AI) program can help doctors identify a rare heart condition called cardiac amyloidosis on routine echocardiograms. The condition causes protein buildup in the heart muscle, leading to heart failure, and is often missed early o…
Matched conditions: HEART FAILURE WITH PRESERVED EJECTION FRACTION (HFPEF
Phase: NA • Sponsor: Germans Trias i Pujol Hospital • Aim: Diagnosis
Last updated Jun 27, 2026 13:06 UTC
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Strength before cardio: new exercise strategy tested for heart patients
Symptom relief Not yet recruitingThis study tests a new exercise approach for people aged 60 and older who have both atrial fibrillation (an irregular heartbeat) and a type of heart failure called HFpEF. Instead of starting with aerobic exercise like walking, participants will first do 2 months of progressive re…
Matched conditions: HEART FAILURE WITH PRESERVED EJECTION FRACTION (HFPEF
Phase: NA • Sponsor: Northwestern University • Aim: Symptom relief
Last updated Jun 27, 2026 12:05 UTC
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Heart failure mystery: 500 patients join hunt for better treatment
Knowledge-focused Not yet recruitingThis study follows 500 people with a type of heart failure called HFpEF, where the heart pumps normally but doesn't fill properly. Researchers will use heart ultrasounds, blood tests, and medical history to group patients into different subtypes. The goal is to better understand …
Matched conditions: HEART FAILURE WITH PRESERVED EJECTION FRACTION (HFPEF
Sponsor: University Of Perugia • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:06 UTC
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Heart fat may melt away after weight loss surgery, study hopes to show
Knowledge-focused Not yet recruitingThis observational study will follow 150 adults with obesity who are already scheduled for bariatric surgery. Researchers will use CT scans and echocardiograms before and about 6 months after surgery to measure fat inside the heart muscle and check how well the heart relaxes. The…
Matched conditions: HEART FAILURE WITH PRESERVED EJECTION FRACTION (HFPEF
Sponsor: Itshak Amsalem • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:29 UTC
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30,000-Person study seeks to unmask hidden heart failure
Knowledge-focused Not yet recruitingThis observational study will enroll 30,000 adults in Denmark to better understand heart failure with preserved ejection fraction (HFpEF), a condition where the heart pumps normally but is too stiff to fill properly. Researchers will use blood tests, heart imaging, and health rec…
Matched conditions: HEART FAILURE WITH PRESERVED EJECTION FRACTION (HFPEF
Sponsor: Herlev and Gentofte Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:00 UTC
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Heart failure patients grouped by data, not drugs
Knowledge-focused Not yet recruitingThis study looks at 200 adults with a type of heart failure called HFpEF. Researchers will use medical records and exercise tests to find different patient groups, or phenotypes. The goal is to better understand these groups, not to test any new treatment. Participants will have …
Matched conditions: HEART FAILURE WITH PRESERVED EJECTION FRACTION (HFPEF
Sponsor: Instituto Politécnico de Leiria • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:08 UTC
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New study aims to decode heart failure using body data
Knowledge-focused Not yet recruitingThis study looks at 600 people (400 with chronic heart failure and 200 healthy) to find patterns in genes, proteins, and gut bacteria that may predict who gets worse. Researchers will track patients for one year to see who is hospitalized or dies. The goal is to create a better r…
Matched conditions: HEART FAILURE WITH PRESERVED EJECTION FRACTION (HFPEF
Sponsor: Xinjiang Medical University • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:12 UTC