Heart fat may melt away after weight loss surgery, study hopes to show

NCT ID NCT07565610

Not yet recruiting Knowledge-focused Sponsor: Itshak Amsalem Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This observational study will follow 150 adults with obesity who are already scheduled for bariatric surgery. Researchers will use CT scans and echocardiograms before and about 6 months after surgery to measure fat inside the heart muscle and check how well the heart relaxes. The goal is to see if losing weight through surgery lowers heart fat and improves diastolic function, which could help prevent heart failure.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If heart fat decreases and function improves after weight loss surgery, this could point toward new ways to prevent or treat heart failure with preserved ejection fraction.
What could go wrong: This is an observational study, not a controlled trial, so it cannot prove cause and effect. Results may not apply to people who do not have surgery or who have different health profiles.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

diastolic heart failure Obesity obesity disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

DIASTOLIC DYSFUNCTION HEART FAILURE WITH PRESERVED EJECTION FRACTION (HFPEF) OBESITY

Contacts and locations

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Study contacts

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Phone: •••-•••-•••• Email: •••••@•••••

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