Pacemaker upgrade could ease stiff heart failure
NCT ID NCT07598760
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This pilot study tests a special pacemaker-like device called Moderato Plus in 20 people with high blood pressure and a type of heart failure where the heart pumps normally but is too stiff (HFpEF). The device delivers Cardiac Neuromodulation Therapy to help control blood pressure and improve heart function during rest and exercise. Participants will be followed for up to 12 months to see if the therapy is feasible and safe.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Moderato Plus device with Cardiac Neuromodulation Therapy (CNT)
- What this could lead to
- If successful, this could point toward a new device-based treatment to improve heart function and blood pressure control in people with HFpEF.
- What could go wrong
- This is a very small pilot study with only 20 participants, so results may not apply to everyone. The device is still experimental, and long-term benefits or risks are unknown.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Georgian Medical Research Clinic Healthycore
Tbilisi, Georgia
-
Tbilisi Heart and Vascular Clinic
Tbilisi, Georgia
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