HEART FAILURE WITH PRESERVED EJECTION FRACTION (HFPEF
Clinical trials for HEART FAILURE WITH PRESERVED EJECTION FRACTION (HFPEF explained in plain language.
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Could a single iron infusion help heart failure patients feel better?
Symptom relief ENROLLING_BY_INVITATIONThis study tests whether a single intravenous dose of iron (ferric derisomaltose) can improve symptoms, exercise ability, and quality of life in 150 adults with a type of heart failure called HFpEF who also have iron deficiency. Participants will receive either the iron infusion …
Matched conditions: HEART FAILURE WITH PRESERVED EJECTION FRACTION (HFPEF
Phase: PHASE2 • Sponsor: Government of Jersey • Aim: Symptom relief
Last updated Jul 02, 2026 05:00 UTC
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Weight-Loss drug semaglutide tested as heart failure treatment
Symptom relief ENROLLING_BY_INVITATIONThis study looks at whether aggressive weight loss using semaglutide can improve symptoms in people with a specific type of heart failure linked to obesity. About 81 participants with a BMI of 30 or higher and heart failure with preserved ejection fraction will receive either sem…
Matched conditions: HEART FAILURE WITH PRESERVED EJECTION FRACTION (HFPEF
Phase: PHASE2 • Sponsor: Mayo Clinic • Aim: Symptom relief
Last updated Jun 27, 2026 09:11 UTC
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Smart workouts aim to boost heart failure Patients' fitness and quality of life
Symptom relief ENROLLING_BY_INVITATIONThis study tests a personalized, remotely monitored exercise program for 150 people with a type of heart failure called HFpEF. The goal is to see if the program improves heart function, muscle health, and quality of life. Participants will follow a structured exercise plan and be…
Matched conditions: HEART FAILURE WITH PRESERVED EJECTION FRACTION (HFPEF
Phase: NA • Sponsor: Universidad Pública de Navarra • Aim: Symptom relief
Last updated Jun 27, 2026 08:00 UTC
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Could a ketone drink boost exercise in heart failure patients?
Symptom relief ENROLLING_BY_INVITATIONThis study tests whether a ketone drink can improve exercise capacity in people with heart failure with preserved ejection fraction (HFpEF). Twenty participants will receive either the ketone drink or a placebo for 8 weeks, then switch. The main goal is to see if the drink helps …
Matched conditions: HEART FAILURE WITH PRESERVED EJECTION FRACTION (HFPEF
Phase: PHASE2 • Sponsor: Duke University • Aim: Symptom relief
Last updated Jun 26, 2026 18:14 UTC
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Can shedding pounds help heart failure patients move better?
Knowledge-focused ENROLLING_BY_INVITATIONThis observational study follows 95 people with heart failure and preserved ejection fraction who are already receiving weight loss treatment as part of their standard care. Researchers will measure muscle blood flow, fat content, and inflammation before and after at least 7% wei…
Matched conditions: HEART FAILURE WITH PRESERVED EJECTION FRACTION (HFPEF
Sponsor: University of Texas Southwestern Medical Center • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:00 UTC
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Heart MRI may unlock secrets of stiff heart failure
Knowledge-focused ENROLLING_BY_INVITATIONThis study looks at whether special heart MRI scans can help predict serious events like death or hospital stays in people with a type of heart failure called HFpEF (heart failure with preserved ejection fraction). Researchers will scan 3000 patients with HFpEF and 500 healthy vo…
Matched conditions: HEART FAILURE WITH PRESERVED EJECTION FRACTION (HFPEF
Sponsor: Chinese Academy of Medical Sciences, Fuwai Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:00 UTC