HEADACHE
Clinical trials for HEADACHE explained in plain language.
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Blood test could help ER doctors spot dangerous headaches faster
Diagnosis CompletedThis study tested if measuring a protein called S100B in the blood could help doctors in the emergency room. The goal was to see if the test could quickly tell the difference between common headaches and headaches caused by a more serious underlying medical problem. Researchers c…
Matched conditions: HEADACHE
Phase: NA • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Diagnosis
Last updated Mar 31, 2026 12:12 UTC
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Eye scan could warn of spinal tap headaches
Diagnosis CompletedThis study tested if a simple, painless ultrasound scan of the eye could help predict which patients might get a specific type of headache after spinal anesthesia for knee replacement surgery. Researchers measured the optic nerve sheath in 176 patients before and after their proc…
Matched conditions: HEADACHE
Sponsor: Ankara City Hospital Bilkent • Aim: Diagnosis
Last updated Mar 13, 2026 15:06 UTC
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Nose drops vs. bed rest: new hope for debilitating spinal headaches?
Symptom relief CompletedThis small pilot study compared two ways to treat a severe headache that can happen if the needle accidentally goes too deep during an epidural. Researchers tested if a simple nasal treatment with numbing medicine worked better than the usual approach of bed rest and extra fluids…
Matched conditions: HEADACHE
Phase: NA • Sponsor: ISSSTE Hospital Regional "Gral. Ignacio Zaragoza" • Aim: Symptom relief
Last updated Mar 31, 2026 12:12 UTC
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Simple IV fluids tested as first step for Kids' severe migraines
Symptom relief CompletedThis study looked at whether giving children intravenous (IV) fluids alone could help reduce severe migraine pain when they visit the emergency department. Researchers wanted to see if the expectation of getting medication influenced pain relief. The goal was to find a simpler, f…
Matched conditions: HEADACHE
Phase: PHASE1, PHASE2 • Sponsor: University of Alberta • Aim: Symptom relief
Last updated Mar 30, 2026 14:33 UTC
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Targeted nerve zap tested for stubborn Neck-Related headaches
Symptom relief CompletedThis study tested a procedure called pulsed radiofrequency to treat headaches that start in the neck (cervicogenic headaches). It was for people whose headaches did not improve enough with standard medications or physical therapy. Doctors used ultrasound to guide the treatment, w…
Matched conditions: HEADACHE
Phase: NA • Sponsor: Ankara City Hospital Bilkent • Aim: Symptom relief
Last updated Mar 27, 2026 12:39 UTC
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Hands-On therapy trial targets jaw pain headaches
Symptom relief CompletedThis study tested different physical therapy approaches to reduce headache pain and improve daily life for people whose headaches are linked to jaw problems. Sixty adults with jaw-related headaches were split into groups to compare standard exercises, hands-on manual therapy, and…
Matched conditions: HEADACHE
Phase: NA • Sponsor: Hasan Kalyoncu University • Aim: Symptom relief
Last updated Mar 25, 2026 14:07 UTC
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Heart drug tested to stop migraine triggers in the brain
Knowledge-focused CompletedThis study tested whether a drug called ivabradine could prevent migraine attacks triggered by another drug, levcromakalim, in people who get migraines without aura. Thirty-seven participants received both drugs in a random order to see if ivabradine reduced the number or severit…
Matched conditions: HEADACHE
Phase: NA • Sponsor: Danish Headache Center • Aim: Knowledge-focused
Last updated Mar 23, 2026 15:17 UTC
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Can walking change your brain? small study investigates link between exercise, fat loss, and brain volume
Knowledge-focused CompletedThis study aimed to understand if a 12-week walking and diet program could change brain structure in overweight adults who also have headaches. Researchers compared 22 participants split into two groups: one did diet and walking, the other diet alone. They used brain scans and bo…
Matched conditions: HEADACHE
Phase: NA • Sponsor: Amasya University • Aim: Knowledge-focused
Last updated Mar 23, 2026 15:16 UTC