New nerve procedure shows promise for stubborn headaches

NCT ID NCT06764433

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested a procedure called pulsed radiofrequency treatment on the greater occipital nerve at the C2 level in 25 people with cervicogenic headache who had not responded to other treatments. The goal was to see if it could reduce headache severity and frequency. The treatment was guided by ultrasound to target the nerve precisely.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
pulsed radiofrequency treatment of the greater occipital nerve
What this could lead to
If it works, this could offer a new option for people with cervicogenic headache who haven't gotten relief from standard treatments.
What could go wrong
This is a small, completed trial with only 25 participants. The results may not apply to everyone, and the procedure carries typical risks of nerve blocks like pain or infection.

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Conditions

The condition(s) this trial relates to.

Headache headache disorder Headache Disorders, Secondary Neck Pain Post-Traumatic Headache

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Health Sciences University, Ankara Bilkent City Hospital

    Ankara, Cankaya, 06800, Turkey (Türkiye)

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