Hands-On therapy may offer Drug-Free relief for Neck-Linked headaches
NCT ID NCT07794319
First seen Aug 31, 2026 · Last updated Sep 01, 2026 · Updated 1 time
Summary
This trial tests whether adding osteopathic care to physiotherapy and pain education reduces headache-related disability in adults with cervicogenic headache, a type of headache caused by neck problems. Researchers will compare three groups: one receiving osteopathic care plus physiotherapy and education, one receiving sham osteopathic care plus the same physiotherapy and education, and one receiving only physiotherapy and education. The study includes 120 adults who have had headaches at least once a week for three months. The main outcome is headache-related disability measured at 6 weeks and again at 24 weeks after treatment.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Osteopathic care (manual therapy) added to physiotherapy and pain education
- What this could lead to
- If it works, adding osteopathic care to standard physiotherapy could offer a drug-free way to reduce headache-related disability in people with cervicogenic headache.
- What could go wrong
- This is a small, early-stage trial, and the sham group helps test whether any benefit comes from the specific technique or just from hands-on attention. Results may not apply to all headache types.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 120 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Nov 2026
An estimate. Start dates often move.
- Expected to finish
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Nov 2028
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * males and females from Rio de Janeiro - RJ - BR * over 18 years old * diagnostic criteria for cervicogenic headache established by the International Classification of Headache Disorders (ICHD-III) * must report episodic headache for at least 3 months, occurring at least once per week * present cervical mobility less than 44° on the cervical flexion-rotation test (CFRT) * exhibit headache during provocative tests at C0, C1, C2, and/or C3 Exclusion Criteria: * undergoing other physiotherapy, osteopathic, orthodontic, or medical treatment * present neurological disorders * have signs of trauma or fracture * report symptoms of vertigo or tinnitus * have another condition that may be the origin of the headache
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Centro Universitário Augusto Motta
Rio de Janeiro, Rio de Janeiro, 21041-020, Brazil
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Neck sense test may forecast headache recovery
- Can Hands-On therapy or targeted exercise ease headaches from the neck?
- Can a physical exam tell a headache from neck pain?
- Could poor posture be fueling teen headaches? a new study investigates
- Can a simple massage tool outperform Hands-On therapy for headaches that start in the neck?
- Headache relief showdown: which neck therapy works best?