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Can a physical exam tell a headache from neck pain?

NCT ID NCT07776275

Knowledge-focused Sponsor: Istanbul Medipol University Hospital Source: ClinicalTrials.gov ↗

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Aug 20, 2026 · Last updated Aug 21, 2026 · Updated 1 time

Summary

This observational study compares physical measures—like posture, grip strength, and neck muscle stiffness—among adults with cervicogenic headache, chronic neck pain, and no pain. The goal is to see if cervicogenic headache has a unique physical profile. Participants attend one 15-minute visit for measurements. No treatment is given. Findings may help guide future diagnosis and therapy research.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If distinct physical traits are found, it could improve how cervicogenic headache is diagnosed and guide future treatment research.
What could go wrong
This is an observational study, so it cannot prove cause and effect. Results may not apply to everyone with these conditions.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 135 people

The number the study aims to enrol. It can still change while the study runs.

Started

Apr 2026

Expected to finish

Oct 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

The study population consists of adults aged 25-60 years recruited at the study site in Istanbul, Türkiye. Participants are classified into three groups according to predefined clinical criteria. The cervicogenic headache group includes individuals diagnosed by a physician according to the International Classification of Headache Disorders, 3rd edition. The chronic nonspecific neck pain group includes individuals with neck pain lasting at least 6 months and no headache. The healthy control group includes individuals without neck pain or headache. Participants receive no study intervention and complete one questionnaire-based and instrument-based assessment session.

Ages

25 to 60 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

* Inclusion Criteria: * Aged 25 to 60 years * Able to provide written informed consent * Meeting the criteria for one of the following groups: * Cervicogenic headache: physician diagnosis according to the International Classification of Headache Disorders, 3rd edition, with symptoms lasting at least 3 months * Chronic nonspecific neck pain: neck pain lasting at least 6 months without headache * Healthy control: no neck pain or headache Exclusion Criteria: * Receipt of physiotherapy for headache or neck pain during the previous 6 months * Diagnosis of a headache disorder other than cervicogenic headache, including migraine or tension-type headache, or a diagnosis of trigeminal neuralgia * History of cervical spine surgery or significant cervical trauma * Current or previous diagnosis of a tumor or cancer * Serious cardiovascular, cerebrovascular, hematological, metabolic, neurological, or psychiatric disorder * Rheumatoid arthritis * Congenital cervical abnormality * Cervical spondylolisthesis or cervical instability * Active infection * Temporomandibular joint dysfunction * Dizziness or visual disturbance accompanying headache * Any clinical red flag suggesting serious cervical pathology * Pregnancy or breastfeeding * Upper-extremity injury, surgery, or another condition affecting handgrip strength * Serious musculoskeletal disorder affecting cervical posture or muscle measurements * Inability to complete the questionnaire-based or instrument-based assessments

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Conditions

The condition(s) this trial relates to.

Post-Traumatic Headache

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Cervicogenic headache Chronic neck pain

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Medipol Sefaköy Üniversite Hastanesi

    RECRUITING

    Istanbul, Sefaköy, 34433, Turkey (Türkiye)

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