Numbing spray in the nose may ease severe headaches after spinal tap mishap
NCT ID NCT07494383
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This pilot study tested a simple procedure called a sphenopalatine ganglion block (SPGB) — applying numbing medicine (lidocaine) inside the nose — against standard care (bed rest and extra fluids) for people who developed a severe headache after an accidental spinal needle puncture. Twenty-six adults took part. The main goal was to see if the study design was practical, not yet to prove the treatment works. Results will help plan a larger trial.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- lidocaine (nasal spray)
- What this could lead to
- If this approach works, it could offer a quick, non-surgical way to relieve severe headaches after accidental spinal needle puncture.
- What could go wrong
- This is a very small pilot study (26 people) testing feasibility, not effectiveness. The nerve block may not work better than simple bed rest and fluids, and it carries rare risks like nosebleed or allergic reaction.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Hospital Regional "General Ignacio Zaragoza," ISSSTE
Mexico City, Mexico City, 09360, Mexico
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Can a numbing nose treatment stop migraine pain in its tracks?
- Could a symptom registry unmask hidden migraine variants?
- Eye-Opening clue: ultrasound of the optic nerve may predict spinal headache after C-Section
- Can a quick neck adjustment change deep headache muscles?
- Real-world study tests migraine drug atogepant over 12 months in tough-to-treat patients
- Could a common numbing drug ease Post-Brain bleed headaches?