HEAD AND NECK CANCER

This was an early-stage study testing a new drug called BDC-3042, both by itself and combined with an existing immunotherapy (cemiplimab), in people with advanced cancers that had stopped responding to standard treatments. The main goals were to find safe doses and see if the tre…

This study aims to find the best way to monitor patients after successful head and neck cancer treatment. It compares the standard schedule of frequent scans and check-ups to a more personalized plan with fewer scheduled visits, focusing instead on tracking patient-reported sympt…

This study tested whether the drug niraparib could help control advanced solid tumors in patients whose cancer has a specific genetic change called a PALB2 mutation. It involved 22 adults with various cancers (like breast, lung, or pancreatic) that had spread or were locally adva…

This study tested whether adding an experimental drug called xevinapant to standard radiotherapy could better prevent cancer from returning in people with high-risk head and neck cancer who had surgery. It focused on patients who could not safely take the usual high-dose chemothe…

This study tested whether combining two drugs, niraparib and dostarlimab, could help control advanced cancers that had specific genetic problems or were previously sensitive to platinum chemotherapy. It involved 51 adults with various cancers, including bladder, stomach, and kidn…

This early-stage study tested whether adding an experimental drug called xevinapant to standard chemotherapy and radiation was safe for people with advanced head and neck cancer. The trial enrolled 18 participants who had not received prior treatment for their cancer. Researchers…

This study tested if a 4-week stop-smoking program before major surgery could reduce complications after the operation. It involved 251 adult smokers scheduled for cancer or other major surgeries. The goal was to see if the structured quitting program led to fewer health problems…

This study tested whether a special weekly dental cleaning and gum treatment could reduce severe mouth sores in people receiving radiation or chemotherapy for head and neck cancer. About 60 participants were randomly assigned to receive either this special cleaning protocol or st…

This study aimed to test a smartphone app designed to help head and neck cancer survivors manage symptoms of depression. Participants were asked to use the mental health app for six weeks and complete surveys. The study was terminated early after enrolling only one person, so its…