HEAD AND NECK CANCER

This early-stage study tested a new drug called BDC-3042, alone or with another drug (cemiplimab), in 17 people with advanced cancers such as breast, kidney, ovarian, head and neck, colorectal, lung, and skin cancer. The main goal was to check safety and find the right dose. The …

This early-phase study tested a new medicine called PF-07921585, given alone or with another drug (sasanlimab), in adults with advanced solid tumors like lung, bladder, kidney, skin, head and neck, or colorectal cancer. The goal was to check safety and how the body handles the dr…

This study tested the drug niraparib in 22 adults with advanced solid tumors (like breast, lung, or pancreatic cancer) that have a specific PALB2 gene mutation. The goal was to see if the drug could shrink tumors or slow cancer growth. The study was stopped early, so results are …

This study tested a combination of two drugs, niraparib and dostarlimab, in adults with advanced solid tumors that had DNA repair problems or were sensitive to platinum chemotherapy. The goal was to see how many patients' tumors shrank or disappeared. The trial was stopped early …

This study tested whether adding the drug xevinapant to standard radiation therapy could help prevent head and neck cancer from coming back after surgery. It included 166 people with a high risk of relapse who could not take the usual chemotherapy drug cisplatin. The trial was st…

This study looked at whether a structured smoking cessation program, started four weeks before surgery, could reduce complications in smokers undergoing intermediate to high-risk operations. Researchers planned to enroll 251 adults who smoked daily and were scheduled for surgerie…

This study tested a new drug called xevinapant combined with chemotherapy and radiation for people with head and neck cancer who cannot take the standard drug cisplatin. The goal was to find the safest dose and see how well the combination works. The study was stopped early, but …

This early-phase study tested whether adding an experimental drug called xevinapant to standard weekly chemotherapy and radiation was safe and tolerable for people with advanced head and neck cancer. It involved 18 participants with cancer that could not be removed by surgery. Th…

This study aimed to see if a mental health app could help head and neck cancer survivors with depression. Participants would use the app for 6 weeks and fill out surveys. However, the study was stopped early and only one person enrolled, so no meaningful results were obtained.

This study tested whether a thorough dental cleaning and mouth treatment could prevent severe mouth sores in people with head and neck cancer getting radiation. About 60 adults were assigned to either the special cleaning or standard brushing. The goal was to see if the cleaning …

This study aimed to find the best way to follow up with patients after they finish curative treatment for head and neck cancer. Researchers compared a personalized follow-up schedule, tailored to each patient's risk, with the standard one-size-fits-all approach. The goal was to s…