Could a common chemo drug boost the benefits of palliative radiation for advanced cancer?

NCT ID NCT03637335

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This phase 3 trial tests whether adding the chemotherapy drug carboplatin to standard palliative radiotherapy helps control tumor growth and reduce pain better than radiotherapy alone. The study includes adults with advanced lung or head and neck cancer who need palliative radiation. Participants receive either radiotherapy plus carboplatin or radiotherapy plus a placebo, and researchers track how long the treated tumors stay under control, pain levels, and quality of life.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
carboplatin
What this could lead to
If it works, this approach could improve pain control and quality of life for people with advanced cancer, and possibly extend survival.
What could go wrong
This is a small early-phase trial, so results may not be conclusive. Adding chemotherapy to radiotherapy can increase side effects like low blood counts and fatigue.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for BRONCHIAL CANCER are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Fabrice Denis

    Le Mans, 72000, France

  • Institut de Cancérologie de l'Ouest

    Nantes, France

More trials for these conditions

Other studies related to the condition(s) this trial covers.