Pfizer tests new drug combo for advanced cancers – but study ends early

NCT ID NCT06580938

Terminated Disease control Sponsor: Pfizer Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This early-phase study tested a new drug called PF-07921585, given alone or with another drug (sasanlimab), in adults with advanced solid tumors like lung, bladder, kidney, melanoma, head & neck, or colorectal cancer. The goal was to check safety and find the right dose. Only 4 people took part before the study was stopped early. This was not a cure trial; it aimed to control the disease and manage side effects.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for BLADDER CANCER are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

colorectal cancer colorectal neoplasm head and neck cancer Head and Neck Neoplasms head and neck squamous cell carcinoma lung neoplasm melanoma non-small cell lung carcinoma renal cell carcinoma urinary bladder carcinoma Urinary Bladder Neoplasms

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

BLADDER CANCER COLORECTAL CANCER HEAD AND NECK CANCER MELANOMA NON-SMALL CELL LUNG CANCER RENAL CELL CARCINOMA

Contacts and locations

Locations

Florida Cancer Specialists Sarasota Drug Development Unit

Sarasota, Florida, 34232, United States
Highlands Oncology Group

Fayetteville, Arkansas, 72703, United States
Highlands Oncology Group

Rogers, Arkansas, 72758, United States
Highlands Oncology Group

Springdale, Arkansas, 72762, United States
Presbyterian/St. Lukes Medical Center

Denver, Colorado, 80218, United States
SCRI Oncology Partners

Nashville, Tennessee, 37203, United States
START Midwest

Grand Rapids, Michigan, 49546, United States
Sarah Cannon Research Institute at HealthONE

Denver, Colorado, 80218, United States
Sarah Cannon Research Institute- Pharmacy

Nashville, Tennessee, 37203, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.