GYNECOLOGIC CANCER

This phase 2 trial tested a combination of two drugs—paclitaxel (given intravenously and directly into the abdomen) and oral nilotinib—in 21 adults with cancers that had spread to the lining of the abdomen and could not be surgically removed. The goal was to see if the treatment …

This study tested three ways of giving the steroid dexamethasone to prevent allergic reactions from the chemotherapy drug paclitaxel in 90 women with breast or gynecologic cancer. One group took oral dexamethasone the night before and morning of treatment, another got it intraven…

This study tested three behavioral approaches—sleep restriction, stimulus control, and systematic light exposure—to help gynecologic cancer survivors who have trouble sleeping. 78 participants completed the program, and researchers measured changes in sleep quality and daytime im…

This study tested a new way to follow up with gynecologic cancer survivors. Instead of seeing a doctor every time, patients saw a nurse at every other visit and used a smartphone app to help manage their health. The goal was to see if this approach improved self-management skills…

This study looked at whether a 10-week pelvic physical therapy program is practical for gynecologic cancer survivors who have sexual problems. Twenty survivors were enrolled to see if they could stick with the program and if it improved their sexual function and quality of life. …

This study tested a program called BOLSTER, designed to give extra support to people with gynecologic or gastrointestinal cancers and their caregivers after a hospital stay. The goal was to see if the program was practical and well-liked. 121 adults with complex care needs took p…

This study tested whether a mobile app helps cancer patients undergoing chemotherapy or radiation therapy report their symptoms more effectively. Over 200 participants used the app to track side effects for 8 weeks. The goal was to see if the app improves how patients recognize a…

This study tested a program to help young couples cope with reproductive and sexual health problems after breast or gynecologic cancer. 158 survivors and their partners took part in a videoconference intervention. The goal was to reduce distress and improve communication about fe…

This study tested whether a combination of slow, guided breathing (called cardiac coherence) and a hypnosis session could help women feel less anxious before breast or gynecologic cancer surgery. Fifty-three women participated, practicing the breathing technique several times a d…

This study tested whether an online education program helps gynecologic cancer patients better manage side effects after brachytherapy. 150 patients were randomly assigned to receive either the online program plus standard care or standard care alone. The goal was to see if the p…

This study tested whether a multimodal prehabilitation program (exercise, nutrition, and education before surgery) could improve outcomes for 140 women undergoing gynecologic cancer surgery. The program was combined with enhanced recovery after surgery (ERAS) care. Researchers me…

This completed phase 3 trial tested whether taking psyllium husk fiber capsules during pelvic radiation therapy could reduce gut inflammation and urgency symptoms. 354 adults with pelvic cancers (like rectal, prostate, or gynecological) took either fiber or placebo capsules daily…

This study tested whether a smartphone app (HOPE or SMART) paired with a Fitbit could help women with recurrent gynecologic cancer manage symptoms and improve quality of life during chemotherapy. 102 women participated, using the app to track symptoms and receive advice, while we…

This study tested whether a peer ambassador program could help more gynecologic cancer patients learn about and join clinical trials. Twenty-three patients with advanced or recurrent gynecologic cancer were paired with a mentor who had personal experience with cancer and clinical…

This completed study followed 40 women who had standard surgery for gynecologic cancers (endometrial, cervical, ovarian, or fallopian tube). Researchers measured changes in quality of life and checked for lower limb lymphedema (leg swelling). The goal was to learn how surgery aff…