Fiber pills may ease radiation side effects for pelvic cancer patients

NCT ID NCT04534075

First seen Jun 24, 2026 · Last updated Jun 26, 2026 · Updated 2 times

Summary

This completed phase 3 trial tested whether taking psyllium husk fiber capsules during pelvic radiation therapy could reduce gut inflammation and urgency symptoms. 354 adults with pelvic cancers (like rectal, prostate, or gynecological) took either fiber or placebo capsules daily. The study measured blood inflammation markers and patient-reported bowel urgency to see if extra fiber helps long-term gut health.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
dietary fiber from psyllium husk
What this could lead to
If it works, this could offer a simple, low-cost way to protect the gut and reduce urgent bowel symptoms during pelvic radiation therapy.
What could go wrong
This is a completed phase 3 trial, but the added fiber might increase acute side effects instead of helping. Results are not yet published, so we don't know if it worked.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Jubileumskliniken, Sahlgrenska University Hospital

    Gothenburg, 413 45, Sweden

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