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Braids and conditioner may boost scalp cooling against chemo hair loss

NCT ID NCT05213936

Recruiting now Symptom relief Sponsor: Montefiore Medical Center Source: ClinicalTrials.gov ↗

First seen Jul 16, 2026 · Last updated Jul 17, 2026 · Updated 1 time

Summary

This study tests whether special hairstyling methods — like braids, cornrows, or a conditioner-and-water mix — can help scalp cooling caps work better to prevent hair loss during chemotherapy. It focuses on people with curly or kinky hair (types 3 and 4), who have been underrepresented in past scalp cooling research. Participants are women with breast, lung, or gynecologic cancer starting taxane-based chemotherapy. The study also looks at long-term hair regrowth and genetic markers linked to scalp cooling success.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
scalp cooling device with hairstyling techniques (braids/cornrows/twists or conditioner/water emulsion)
What this could lead to
If successful, this could make scalp cooling more effective for people with curly or kinky hair, reducing chemotherapy-related hair loss in a group often underrepresented in prior studies.
What could go wrong
This is a small, early-stage study with only 41 participants, so results may not apply to everyone. The techniques may not work for all hair types or chemotherapy regimens.

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Conditions

The condition(s) this trial relates to.

alopecia breast cancer female reproductive organ cancer non-small cell lung carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ALOPECIA

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Montefiore Medical Center

    RECRUITING

    The Bronx, New York, 10461, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

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