GLIOMA
Clinical trials for GLIOMA explained in plain language.
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New way to deliver chemo directly to brain tumors tested in small study
Disease control TerminatedThis early-phase trial tested a single dose of the cancer drug temsirolimus, given directly into the brain's blood supply, for people with recurrent high-grade glioma (a fast-growing brain tumor). Only 5 participants were enrolled, and the study was terminated early. The main goa…
Matched conditions: GLIOMA
Phase: EARLY_PHASE1 • Sponsor: Nader Sanai • Aim: Disease control
Last updated Jun 27, 2026 12:33 UTC
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Experimental combo therapy for brain cancer shows promise in early trial
Disease control TerminatedThis study tested a special type of radiation (pulse reduced dose rate) combined with the drug bevacizumab in 49 people with recurrent high-grade gliomas (brain tumors). The goal was to see if this combination could help patients live longer. Participants received radiation over …
Matched conditions: GLIOMA
Phase: PHASE2 • Sponsor: University of Wisconsin, Madison • Aim: Disease control
Last updated Jun 27, 2026 12:00 UTC
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Brain cancer drug trial halted after just two patients
Disease control TerminatedThis study tested a new drug called VAL-083 in people with glioblastoma, an aggressive brain cancer that had returned after standard treatments. The trial aimed to see if VAL-083 could help patients live longer. However, the study was stopped early after only 2 people enrolled, s…
Matched conditions: GLIOMA
Phase: PHASE3 • Sponsor: DelMar Pharmaceuticals, Inc. • Aim: Disease control
Last updated Jun 26, 2026 13:46 UTC
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Wakefulness drug shows promise for brain tumor fatigue, but study stalls
Symptom relief TerminatedThis study tested a drug called solriamfetol to see if it could safely help people with brain tumors (gliomas) feel more awake, think clearer, and have a better quality of life. Only 2 people enrolled before the study was stopped early. The main goal was to check for serious side…
Matched conditions: GLIOMA
Phase: PHASE2 • Sponsor: Wake Forest University Health Sciences • Aim: Symptom relief
Last updated Jun 27, 2026 07:55 UTC
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Ultrasound dye may help brain surgeons spot hidden tumor edges
Knowledge-focused TerminatedThis study tested whether injecting a contrast dye and using ultrasound during brain tumor surgery could help surgeons see the difference between tumor and healthy brain tissue. The goal was to remove more of the tumor safely. Only 2 people were enrolled before the study was stop…
Matched conditions: GLIOMA
Phase: EARLY_PHASE1 • Sponsor: University of Colorado, Denver • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:01 UTC
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Antifungal drug tested against brain tumors – trial stopped early
Knowledge-focused TerminatedThis early-phase trial tested whether the antifungal drug ketoconazole could block a protein called tGLI1 in brain tumors. It included 15 people with breast cancer that spread to the brain or with a type of brain cancer called glioma. The study was terminated early, so we have li…
Matched conditions: GLIOMA
Phase: EARLY_PHASE1 • Sponsor: Wake Forest University Health Sciences • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:03 UTC
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Brain tumor drug penetration study halted early
Knowledge-focused TerminatedThis early-phase trial aimed to measure how much of the drug infigratinib reaches brain tumor tissue in people with recurrent high-grade glioma (a type of brain cancer). Only 7 participants were enrolled before the study was terminated. The main goal was to check drug levels in t…
Matched conditions: GLIOMA
Phase: EARLY_PHASE1 • Sponsor: Nader Sanai • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:55 UTC
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Brain tumor study looks at tiny molecule as possible clue
Knowledge-focused TerminatedThis study looked at a tiny molecule called microRNA-10b in people with brain tumors called gliomas. Researchers wanted to see if higher levels of this molecule could help predict how the disease might progress or how long patients might live. The study was stopped early, but it …
Matched conditions: GLIOMA
Sponsor: Dartmouth-Hitchcock Medical Center • Aim: Knowledge-focused
Last updated Jun 26, 2026 17:16 UTC