Ultrasound dye may help brain surgeons spot hidden tumor edges

NCT ID NCT07050836

Terminated Knowledge-focused Sponsor: University of Colorado, Denver Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested whether injecting a contrast dye and using ultrasound during brain tumor surgery could help surgeons see the difference between tumor and healthy brain tissue. The goal was to remove more of the tumor safely. Only 2 people were enrolled before the study was stopped early, so the results are very limited.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Definity contrast agent
What this could lead to: If successful, this approach could help surgeons remove more tumor tissue during brain surgery, potentially improving outcomes for glioma patients.
What could go wrong: This was a very early, tiny study (only 2 people) that was terminated early, so we have very little data. The technique may not work better than current methods.

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Conditions

The condition(s) this trial relates to.

brain cancer brain glioma glioma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

GLIOMA GLIOMA (ANY GRADE) IN THE BRAIN

Contacts and locations

Locations

University of Colorado Anschutz Medical Campus

Aurora, Colorado, 80045, United States

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