Brain surgery gets a GPS: network maps may help remove tumors while preserving function

NCT ID NCT07717827

First seen Jul 21, 2026 · Last updated Jul 22, 2026 · Updated 1 time

Summary

This study tests a new way to plan brain tumor surgery by creating detailed maps of each patient's brain networks using advanced MRI. Instead of relying only on standard anatomy, surgeons can see the white matter pathways and functional networks that could be affected. The goal is to remove as much tumor as possible while reducing the risk of neurological damage. The study includes 400 adults with gliomas or brain metastases in critical brain areas.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
connectome-guided network-based neuronavigation and advanced diffusion MRI tractography pipeline
What this could lead to
If successful, this approach could help surgeons remove more tumor while better protecting brain functions, potentially improving recovery and quality of life for patients with brain tumors in critical areas.
What could go wrong
This is a single-center study, and the technique may not work for all tumor types or locations. The added complexity could also increase surgery time or introduce new risks.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Unit of Neurosurgery - A.R.N.A.S. Civico Di Cristina Benfratelli - 90127, Palermo - Italy

    RECRUITING

    Palermo, PA, 90127, Italy

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact

    Contact

    Contact

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