BRAIN METASTASASES
Clinical trials for BRAIN METASTASASES explained in plain language.
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New combo attack on aggressive breast cancer brain tumors shows promise in early trial
Disease control Recruiting nowThis study tests whether combining radiation therapy with three drugs (platinum chemotherapy, adebrelimab, and bevacizumab) can control brain metastases from triple-negative breast cancer. About 58 adults aged 18-70 with this specific type of advanced breast cancer will receive t…
Matched conditions: BRAIN METASTASASES
Phase: PHASE2 • Sponsor: Fudan University • Aim: Disease control
Last updated Jun 27, 2026 14:00 UTC
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Experimental combo targets Hard-to-Treat cancers
Disease control Recruiting nowThis early-phase study is testing two drugs together — alpelisib and pembrolizumab — in people with metastatic breast cancer or melanoma that has spread to the brain or other organs. The main goal is to find a safe dose and see what side effects occur. Up to 50 adults whose cance…
Matched conditions: BRAIN METASTASASES
Phase: PHASE1 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated Jun 27, 2026 12:08 UTC
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New smart drug takes aim at Hard-to-Treat brain cancers
Disease control Recruiting nowThis early-phase trial is testing an investigational drug called risvutatug rezetecan in 15 people with recurrent glioblastoma or brain metastases. The drug is designed to seek out and deliver a cancer-killing payload to tumor cells. The study first measures how much drug gets in…
Matched conditions: BRAIN METASTASASES
Phase: EARLY_PHASE1 • Sponsor: Nader Sanai • Aim: Disease control
Last updated Jun 27, 2026 09:10 UTC
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Can a cancer drug beat steroids for brain radiation injury?
Disease control Recruiting nowThis study compares bevacizumab (Avastin) to standard steroid treatment (dexamethasone) as the first therapy for people with brain radiation necrosis—a side effect of radiation therapy for brain tumors. About 408 participants with high-grade glioma or brain metastases will be ran…
Matched conditions: BRAIN METASTASASES
Phase: PHASE3 • Sponsor: The Netherlands Cancer Institute • Aim: Disease control
Last updated Jun 27, 2026 09:07 UTC
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New combo radiation therapy aims to tame large brain tumors
Disease control Recruiting nowThis study tests a new way to treat large brain tumors using two different radiation machines. Patients get four daily treatments with a linear accelerator, then a break, followed by one precise Gamma Knife treatment. The goal is to better control tumors while protecting healthy …
Matched conditions: BRAIN METASTASASES
Phase: PHASE2 • Sponsor: Sunnybrook Health Sciences Centre • Aim: Disease control
Last updated Jun 26, 2026 15:18 UTC
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Spinal tap could spot hidden brain cancers
Knowledge-focused Recruiting nowThis pilot study is exploring whether a one-time sample of spinal fluid (taken via a lumbar puncture) can detect cancer DNA in patients with solid tumors that have spread to the brain or spinal cord. Researchers will enroll 60 participants across three groups: those with leptomen…
Matched conditions: BRAIN METASTASASES
Phase: NA • Sponsor: Sunnybrook Health Sciences Centre • Aim: Knowledge-focused
Last updated Jun 28, 2026 00:00 UTC