Spinal tap could spot hidden brain cancers

This pilot study is exploring whether a one-time sample of spinal fluid (taken via a lumbar puncture) can detect cancer DNA in patients with solid tumors that have spread to the brain or spinal cord. Researchers will enroll 60 participants across three groups: those with leptomeningeal disease, those with brain metastases, and those with no brain involvement. The goal is to see if this liquid biopsy approach is feasible and can identify tumor biomarkers in the cerebrospinal fluid.