FAMILIAL ADENOMATOUS POLYPOSIS
Clinical trials for FAMILIAL ADENOMATOUS POLYPOSIS explained in plain language.
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New drug aims to shrink polyps in inherited colon cancer condition
Disease control Recruiting nowThis study tests an experimental drug called REC-4881 in 67 adults with familial adenomatous polyposis (FAP), a genetic condition that causes many polyps in the colon and small intestine. The goal is to see if the drug can safely reduce the number and size of polyps, helping cont…
Matched conditions: FAMILIAL ADENOMATOUS POLYPOSIS
Phase: PHASE1, PHASE2 • Sponsor: Recursion Pharmaceuticals Inc. • Aim: Disease control
Last updated Jun 27, 2026 13:02 UTC
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Tailored scope schedule aims to cut cancer risk in FAP patients
Disease control Recruiting nowThis study tests a personalized surveillance plan for people with familial adenomatous polyposis (FAP) who have had their colon removed. Instead of a fixed schedule, the timing of follow-up endoscopies (every 6 months to 2 years) is based on each person's polyp burden and past tr…
Matched conditions: FAMILIAL ADENOMATOUS POLYPOSIS
Sponsor: Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) • Aim: Disease control
Last updated Jun 27, 2026 09:07 UTC
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Tailored scope schedule may cut cancer risk in FAP patients
Disease control Recruiting nowThis study tests a personalized surveillance plan for people with familial adenomatous polyposis (FAP), a condition that raises the risk of polyps and cancer in the stomach and duodenum. Participants will have endoscopic exams at intervals tailored to their polyp severity, rangin…
Matched conditions: FAMILIAL ADENOMATOUS POLYPOSIS
Sponsor: Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) • Aim: Disease control
Last updated Jun 27, 2026 09:07 UTC
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Could a simple ketone drink reduce the need for surgery in FAP patients?
Disease control Recruiting nowThis study tests whether a daily ketone supplement (BHB) is safe and tolerable for people with Familial Adenomatous Polyposis (FAP), a genetic condition that causes many colon polyps and often leads to surgery. Twenty participants will take the supplement for two weeks to see if …
Matched conditions: FAMILIAL ADENOMATOUS POLYPOSIS
Phase: NA • Sponsor: Abramson Cancer Center at Penn Medicine • Aim: Disease control
Last updated Jun 26, 2026 13:57 UTC
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Could a Cancer-Killing pill stop colon cancer before it starts?
Prevention Recruiting nowThis early-phase study tests the safety of a drug called ONC201 (dordaviprone) in 36 adults at high risk for colorectal cancer due to familial adenomatous polyposis (FAP) or a history of many polyps. The drug aims to kill precancerous cells without harming normal ones. Researcher…
Matched conditions: FAMILIAL ADENOMATOUS POLYPOSIS
Phase: PHASE1 • Sponsor: National Cancer Institute (NCI) • Aim: Prevention
Last updated Jun 27, 2026 13:07 UTC
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Home treadmill trial hopes to stop polyp return in rare genetic condition
Prevention Recruiting nowThis study tests different amounts of exercise to see if it can prevent colorectal polyps from returning in people with Familial Adenomatous Polyposis (FAP). About 32 participants will follow a personalized treadmill program at home for 26 weeks. Researchers will check how well p…
Matched conditions: FAMILIAL ADENOMATOUS POLYPOSIS
Phase: NA • Sponsor: University of Michigan Rogel Cancer Center • Aim: Prevention
Last updated Jun 27, 2026 12:36 UTC
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Massive cancer database aims to unlock secrets of the disease
Knowledge-focused Recruiting nowThis study is building a huge registry of information and biological samples from adults with or at risk for many types of cancer, as well as healthy volunteers. Researchers will use this resource to study what causes cancer and how to better prevent, detect, and treat it. The re…
Matched conditions: FAMILIAL ADENOMATOUS POLYPOSIS
Sponsor: University of Nebraska • Aim: Knowledge-focused
Last updated Jul 01, 2026 00:00 UTC
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Hunt for hidden cancer genes: families needed to unlock hereditary secrets
Knowledge-focused Recruiting nowThis study aims to discover new genes that may cause certain cancers to run in families. Researchers will collect blood samples and health information from 1,500 people in families where multiple members have had cancer, especially childhood cancers. The goal is to build a regist…
Matched conditions: FAMILIAL ADENOMATOUS POLYPOSIS
Sponsor: St. Jude Children's Research Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:00 UTC
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Gut bacteria may influence polyp risk in inherited colon condition
Knowledge-focused Recruiting nowThis study looks at how gut microbes and environmental factors affect polyp development in people with familial adenomatous polyposis (FAP), a genetic condition that causes many colon polyps and often leads to cancer. Researchers will collect stool, blood, and duodenal fluid samp…
Matched conditions: FAMILIAL ADENOMATOUS POLYPOSIS
Sponsor: Hospices Civils de Lyon • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:37 UTC
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New tool could better predict duodenal cancer in FAP patients
Knowledge-focused Recruiting nowThis study aims to create a more accurate way to predict duodenal cancer risk in people with familial adenomatous polyposis (FAP), a genetic condition that greatly increases the chance of developing this cancer. Researchers will analyze endoscopy images from 300 participants to d…
Matched conditions: FAMILIAL ADENOMATOUS POLYPOSIS
Sponsor: Fondazione IRCCS Istituto Nazionale dei Tumori, Milano • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:52 UTC