New drug aims to shrink polyps in inherited colon cancer condition
NCT ID NCT05552755
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests an experimental drug called REC-4881 in 67 adults with familial adenomatous polyposis (FAP), a genetic condition that causes many polyps in the colon and small intestine. The goal is to see if the drug can safely reduce the number and size of polyps, helping control the disease. Participants must be 18 or older, have had their colon removed, and have moderate to severe polyps in the duodenum or remaining bowel.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Benaroya Research Institute at Virginia Mason
RECRUITINGSeattle, Washington, 98101, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact Email: •••••@•••••
Contact
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Corewell Health (Spectrum Health Hospitals Colorectal Cancer Multis)
ACTIVE_NOT_RECRUITINGGrand Rapids, Michigan, 49503, United States
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Del Sol Research Management
WITHDRAWNTucson, Arizona, 85715, United States
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Digestive and Liver Center of Florida
TERMINATEDOrlando, Florida, 32825, United States
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GI Pros
WITHDRAWNNaples, Florida, 34102, United States
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Gastro One-8110 Walnut Rs
TERMINATEDCordova, Tennessee, 38108, United States
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Gastroenterology Health Partners, PLLC
WITHDRAWNNew Albany, Indiana, 47150, United States
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Genetic Cancer Prevention Clinic - UT Southwestern
RECRUITINGDallas, Texas, 75390, United States
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Huntsman Cancer Institute and University of Utah
RECRUITINGSalt Lake City, Utah, 84112, United States
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
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MD Anderson Cancer Center
RECRUITINGHouston, Texas, 77030, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
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Mayo Clinic - Rochester
ACTIVE_NOT_RECRUITINGRochester, Minnesota, 55905, United States
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Mayo Clinic - Scottsdale
ACTIVE_NOT_RECRUITINGScottsdale, Arizona, 85259, United States
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Medical Associates Research Group
WITHDRAWNSan Diego, California, 92123, United States
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Tandem Clinical Research
TERMINATEDMarrero, Louisiana, 70072, United States
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University of Pennsylvania
RECRUITINGPhiladelphia, Pennsylvania, 19104, United States
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Vanderbilt Digestive Center
RECRUITINGNashville, Tennessee, 37232, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Washington University School of Medicine
RECRUITINGSt Louis, Missouri, 63110, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact