Gut bacteria may influence polyp risk in inherited colon condition

NCT ID NCT06614738

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looks at how gut microbes and environmental factors affect polyp development in people with familial adenomatous polyposis (FAP), a genetic condition that causes many colon polyps and often leads to cancer. Researchers will collect stool, blood, and duodenal fluid samples from 100 adults who have had their colon removed. They will also track diet and lifestyle. The goal is to find microbial patterns linked to polyp growth, which could lead to better monitoring or prevention strategies.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to

If successful, this could help identify bacterial or lifestyle factors that influence polyp development, potentially guiding future prevention strategies.

What could go wrong

This is an observational study, not a treatment trial. It will not directly benefit participants and may not yield clear or actionable results.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Adenomatous Polyposis Coli classic familial adenomatous polyposis colorectal neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Hôpital Edouard Herriot

    RECRUITING

    Lyon, France, 69003, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Hôpital de la Croix Rousse

    RECRUITING

    Lyon, France, 69004, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••