Gut bacteria may influence polyp risk in inherited colon condition
NCT ID NCT06614738
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study looks at how gut microbes and environmental factors affect polyp development in people with familial adenomatous polyposis (FAP), a genetic condition that causes many colon polyps and often leads to cancer. Researchers will collect stool, blood, and duodenal fluid samples from 100 adults who have had their colon removed. They will also track diet and lifestyle. The goal is to find microbial patterns linked to polyp growth, which could lead to better monitoring or prevention strategies.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- What this could lead to
- If successful, this could help identify bacterial or lifestyle factors that influence polyp development, potentially guiding future prevention strategies.
- What could go wrong
- This is an observational study, not a treatment trial. It will not directly benefit participants and may not yield clear or actionable results.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for FAMILIAL ADENOMATOUS POLYPOSIS are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Hôpital Edouard Herriot
RECRUITINGLyon, France, 69003, France
-
Hôpital de la Croix Rousse
RECRUITINGLyon, France, 69004, France
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Can a freezing balloon zap away precancerous gut growths?
- Study checks if stopping a drug made polyps grow faster
- Could a common drug curb polyps in teens with rare genetic condition?
- Can pelvic floor exercises help pouch patients regain control?
- New drug E7386 tested for tough cancers
- Large study looks at how a 25-Gene cancer test affects patients and families